Bioinformatics analysis of candidate genes for milk production traits in water buffalo (Bubalus bubalis)
文献类型： 外文期刊
第一作者： Du, C.
作者： Du, C.;Deng, T. X.;Zhou, Y.;Hua, G. H.;Du, C.;Deng, T. X.;Zhou, Y.;Hua, G. H.;Deng, T. X.;Ghanem, N.;Hua, G. H.
作者机构：
关键词： GOanalysis; KEGG pathway; PPI network; Function module
期刊名称：TROPICAL ANIMAL HEALTH AND PRODUCTION （ 影响因子：1.559； 五年影响因子：1.681 ）
ISSN： 0049-4747
年卷期： 2020 年 52 卷 1 期
页码：
收录情况： SCI
摘要： Water buffalo (Bubalus bubalis) is an important livestock species in developing countries due to its contribution to meat, milk production, and a certain form of labor. However, the genetic potential of buffalo milk production traits has not been fully exploited. To date, 516 candidate genes associated with milk production traits of buffalo have been identified. The present study aimed to explore the possible molecular mechanisms underlying milk production traits of this species through functional genomics analysis of these candidate genes by using different bioinformatics tools. Gene ontology (GO) analysis indicated that these candidate genes were associated with complex biological processes, such as cell proliferation and mitotic nuclear division. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis demonstrated that these candidate genes were enriched in multiple signaling pathways, such as AMPK, ErbB, Toll-like receptor, and Jak-STAT. In addition, one function module consisting of 57 nodes and 139 edges were identified from the protein-protein interaction (PPI) network. GO analysis showed that the 57 candidate genes in this function module were enriched in three main biological processes, including homeostasis, metabolism, and cell response. These three distinct biological processes are well known for regulating mammary gland activities, which explained clearly the mechanism underlying milk production traits. This study provides a novel perspective for better understanding of the biological processes linked with milk production traits. This knowledge is conducive to the improvement of milk yield and composition of this species.
分类号：
- 相关文献
作者其他论文 更多>>
-
Genomic insights into selection signatures and candidate genes for milk production traits in buffalo population
作者：Deng, T. X.;Ma, X. Y.;Duan, A. Q.;Lu, X. R.;Abdel-Shafy, H.
关键词：Integrated haplotype score; Quantitative trait loci; Runs of homozygosity; Transcriptomics; Whole-genome resequencing
-
Morpho-molecular characterization and pathogenicity of fungi associated with sweet cherry (Prunus avium) trunk diseases in China
作者：Zhang, W.;Chen, P.;Zhou, Y.;Ji, S.;Li, X.;Abeywickrama, P. D.;Yan, J.;Zhou, Y.;Hyde, K. D.;Zhou, Y.;Hyde, K. D.;Hyde, K. D.;Hyde, K. D.
关键词：Fungal taxonomy; Fusarium oxysporum species complex; Koch's postulates; Monilinia; Trunk diseases
-
Effects of Biochar and α-Fe2O3 Nanoparticles on the Growth, Photosynthetic Apparatus and Fruit Quality of Medicinal Plant Muskmelon
作者：Wang, Y.;Zhou, W.;Yi, L.;Dai, Z.;Qiu, L.;Zhou, Y.;Wang, S.;Li, H.;Li, J.;Wang, Y.;Zhou, W.;Yi, L.;Dai, Z.
关键词：Cucumis melo; alpha-Fe2O3 nanoparticles; biochar; medicinal ingredients; muskmelon; fruit quality
-
Transcriptomic Analysis of the Primary Roots of Dandelion (Taraxacum mongolicum Hand.-Mazz.) in Response to Salt Stress
作者：Zhang, L.;Zhou, Y.;Lu, Y.;Wang, X.;Zhang, S.;Duan, Y.;Ma, C.;Wang, X.;Chen, G.;Feng, W.;Wang, X.;Xue, Z.;Wang, X.
关键词：salt stress; dandelion; seedling stage; root organ; transcriptome
-
Simultaneous quantification of oxyclozanide and levamisole in milk via ultra-high-performance liquid chromatography tandem mass spectrometry: A validated high-sensitivity approach for veterinary residue surveillance
作者：Dai, G.;Sun, K.;Zhou, Y.;Li, B.;Wang, Q.;Qiu, Y.;Zhou, X.;Zhang, J.;Dai, G.;Sun, K.;Zhang, J.;Peng, X.
关键词：veterinary drug residues; UPLC-MS/MS; food safety; antiparasitic agents; milk
-
Hydroponic barley supplementation fed with high-protein diets improves the production performance of lactating dairy cows
作者：Wu, Z. H.;Du, C.;Hou, M. J.;Zhao, L. S.;Ma, L.;Bu, D. P.;Sinclair, L. A.;Bu, D. P.;Bu, D. P.
关键词：dairy cow; dietary protein; feed efficiency; hydroponic barley; nitrogen utilization
-
The Effect of a-Fe2O3 Nanoparticles on the Physiological Characteristics and Active Ingredients of Muskmelon on the Cadmium-Polluted Soil
作者：Zou, Z.;Zhou, Y.;Hao, Y.;Li, J.;Qi, M.;Qiu, L.;Cheng, Y.;Wang, Y.;Dai, Z.;Wang, Y.;Dai, Z.
关键词：Cucumis melo L.; soil cadmium pollution; muskmelon; & alpha;-Fe2O3 nanoparticles; growth parameters; antioxidant system; active ingredients
