Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
文献类型: 外文期刊
第一作者: An, Tong-Qing
作者: An, Tong-Qing;Li, Jiang-Nan;Su, Chia-Ming;Yoo, Dongwan
作者机构:
期刊名称:VIRUS RESEARCH ( 影响因子:3.303; 五年影响因子:3.445 )
ISSN: 0168-1702
年卷期: 2020 年 286 卷
页码:
收录情况: SCI
摘要: Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous amounts of economic losses to the swine industry for more than three decades, but its control is still unsatisfactory. A significant amount of information is available for host cell-virus interactions during infection, and it is evident that PRRSV has evolved to equip various strategies to disrupt the host antiviral system and provide favorable conditions for survival. The current study reviews viral strategies for modulations of cellular processes including innate immunity, apoptosis, microRNAs, inflammatory cytokines, and other cellular pathways.
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