Animal coronaviruses and SARS-CoV-2

文献类型： 外文期刊

第一作者： Zhang, Guangzhi

作者： Zhang, Guangzhi;Qin, Tong;Jia, Yaxiong;Cui, Shangjin;Zhang, Guangzhi;Qin, Tong;Cui, Shangjin;Li, Bin;Yoo, Dongwan;Zhang, Xiaodong;Zhang, Xiaodong

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关键词： animal coronaviruses; SARS-CoV-2; tissue host tropism; viral evolution; zoonotic coronavirus

期刊名称：TRANSBOUNDARY AND EMERGING DISEASES （ 影响因子：5.005； 五年影响因子：4.622 ）

ISSN： 1865-1674

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收录情况： SCI

摘要： COVID-19 is a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has rapidly spread to 216 countries and territories since first outbreak in December of 2019, posing a substantial economic losses and extraordinary threats to the public health worldwide. Although bats have been suggested as the natural host of SARS-CoV-2, transmission chains of this virus, role of animals during cross-species transmission, and future concerns remain unclear. Diverse animal coronaviruses have extensively been studied since the discovery of avian coronavirus in 1930s. The current article comprehensively reviews and discusses the current understanding about animal coronaviruses and SARS-CoV-2 for their emergence, transmission, zoonotic potential, alteration of tissue/host tropism, evolution, status of vaccines and surveillance. This study aims at providing guidance for control of COVID-19 and preventative strategies for possible future outbreaks of zoonotic coronavirus via cross-species transmission.

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