Gallic acid as a key substance to inhibit proliferation and adipogenesis in bovine subcutaneous adipocyte

文献类型： 外文期刊

第一作者： Jin, Qing

作者： Jin, Qing;Liu, Guifen;Tan, Xiuwen;Zhang, Xianglun;Liu, Xiaomu;Wei, Chen

作者机构：

关键词： Gallic acid; bovine; subcutaneous adipocyte; proliferation; adipogenesis

期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：2.282； 五年影响因子：1.702 ）

ISSN： 1049-5398

年卷期：

页码：

收录情况： SCI

摘要： Gallic acid (GA) is a widespread naturally occurring phenolic acid and one of the main active monomers that forms polyphenols such as tannins. In recent years, GA has been found as a potential regulator in lipid metabolism. However, effects and possible mechanisms of GA on cell growth and lipid metabolism of bovine subcutaneous adipocytes remain unknown. In this study, we investigated whether GA could affect proliferation and adipogenesis of subcutaneous adipocyte in beef cattle. We found that GA possesses inhibitive effects on proliferation and adipogenesis of bovine subcutaneous adipocyte via activating the metabolic master factor AMP-activated protein kinase alpha (AMPK alpha) to promote programmed cell death and lipolysis. The findings prove GA is a key substance to inhibit proliferation and adipogenesis of bovine subcutaneous adipocytein vitro. Furtherin vivostudy needs conducted to verify the reductive effects of GA on subcutaneous fat in beef cattle.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Isobutyramide and Slow-Release Urea as Substitutes for Soybean Meal in the Finishing Diet of Beef Cattle

    作者：Wei, Chen;Tao, Haiying;Liu, Guifen;Tian, Kechuan;Wei, Chen;Tao, Haiying;Liu, Guifen;Tian, Kechuan

    关键词：isobutyramide; slow-release urea; soybean meal; beef cattle

  • MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development

    作者：He, Junmin;Wei, Chen;Zhang, Guoping;Mao, Jingyi;Tian, Kechuan;Liu, Guifen;He, Junmin;Wei, Chen;Zhang, Guoping;Tian, Kechuan;Liu, Guifen;Huang, Xixia;Li, Xue;Yang, Cunming;Zhang, Wenjing

    关键词：hair follicle development; sheep dermal fibroblasts; cotargeting; proliferation; migrate; apoptosis

  • Estimation of Genetic Parameters for Early Growth Traits in Luzhong Mutton Sheep

    作者：Ren, Yifan;Li, Xue;He, Junmin;Liu, Guifen;Wei, Chen;Zhang, Guoping;Zhang, Wenhao;Nie, Fumei;Tian, Kechuan;Ren, Yifan;Li, Xue;Zhang, Menghua;Zhang, Wenhao;Nie, Fumei;Wang, Ming;Huang, Xixia

    关键词：animal model; early growth traits; genetic parameters; maternal effects; Luzhong mutton sheep

  • A compendium of genetic regulatory effects across pig tissues

    作者：Teng, Jinyan;Gao, Yahui;Xu, Zhiting;Lin, Qing;Diao, Shuqi;Pan, Xiangchun;Wei, Chen;Zhang, Zhe;Zhang, Zhe;Gao, Yahui;Li, Cong-jun;Liu, George E.;Gao, Yahui;Gao, Yahui;Yin, Hongwei;Bai, Lijing;Yang, Liu;Yi, Guoqiang;Tang, Zhonglin;Li, Kui;Yin, Hongwei;Bai, Zhonghao;Bai, Zhonghao;Yu, Xiaoshan;Haley, Chris;Navarro, Pau;Tenesa, Albert;Fang, Lingzhao;Liu, Shuli;Zhao, Bingru;Yang, Wenjing;Ding, Xiangdong;Li, Xiujin;Pan, Zhangyuan;Yang, Wenjing;Guan, Dailu;Pan, Zhangyuan;Hou, Yali;Hou, Yali;Keel, Brittney N.;Rohrer, Gary A.;Lindholm-Perry, Amanda K.;Oliver, William T.;Ballester, Maria;Crespo-Piazuelo, Daniel;Quintanilla, Raquel;Rawlik, Konrad;Xia, Charley;Xia, Charley;Yao, Yuelin;Yao, Wenye;Karlskov-Mortensen, Peter;Fredholm, Merete;Amills, Marcel;Clop, Alex;Amills, Marcel;Godia, Marta;Clop, Alex;Giuffra, Elisabetta;Rocha, Dominique;Wang, Sheng;Rocha, Dominique;Dekkers, Jack C. M.;Kramer, Luke;Tuggle, Christopher K.;Corbett, Ryan;Charles, Mathieu;Pausch, Hubert;Hu, Xiaoxiang;Frantz, Laurent;Frantz, Laurent;Luo, Yonglun;Lin, Lin;Luo, Yonglun;Lin, Lin;Luo, Yonglun;Zhang, Zhe;Chen, Zitao;Cui, Leilei;Cui, Leilei;Cui, Leilei;Cui, Leilei;Cui, Leilei;Xiang, Ruidong;Xiang, Ruidong;Shen, Xia;Shen, Xia;Shen, Xia;Li, Pinghua;Huang, Ruihua;Tang, Guoqing;Li, Mingzhou;Zhao, Yunxiang;Jiang, Jicai;Yuan, Xiaolong;Liu, Xiaohong;Zhao, Shuhong;Zhao, Pengju;Zhao, Shuhong;Zhao, Pengju;Zhao, Pengju;Haley, Chris;Tenesa, Albert;Zhang, Qin;Tenesa, Albert

    关键词：

  • Genome-Wide DNA Methylation Analysis and Functional Validation of Litter Size Traits in Jining Grey Goats

    作者：Yang, Cunming;Ren, Yifan;Huang, Xixia;Yang, Cunming;He, Junmin;Mao, Jingyi;Ren, Yifan;Liu, Guifen;Wei, Chen;Zhang, Guoping;Tian, Kechuan

    关键词：DNA methylation; gene expression; goat ovary; prolificacy

  • Multiomics analyses of Jining Grey goat and Boer goat reveal genomic regions associated with fatty acid and amino acid metabolism and muscle development

    作者：Liu, Zhaohua;Tan, Xiuwen;Jin, Qing;Cui, Xukui;Wang, Jianying;Meng, Xianfeng;Zhu, Rongsheng;Wang, Ke;Liu, Zhaohua;Tan, Xiuwen;Cui, Xukui;Wang, Jianying;Meng, Xianfeng;Zhu, Rongsheng;Wang, Ke;Zhan, Wangtao;Liu, Gang

    关键词：Goat; Meat Quality; Muscle Development; RNA-seq; Selective Signature

  • PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs

    作者：Zeng, Haonan;Zhang, Wenjing;Lin, Qing;Gao, Yahui;Teng, Jinyan;Xu, Zhiting;Cai, Xiaodian;Zhong, Zhanming;Wu, Jun;Liu, Yuqiang;Diao, Shuqi;Wei, Chen;Gong, Wentao;Pan, Xiangchun;Li, Zedong;Huang, Xiaoyu;Chen, Xifan;Du, Jinshi;Li, Jiaqi;Yuan, Xiaolong;Zhang, Zhe;Zhao, Fuping;Zhao, Yunxiang;Ballester, Maria;Crespo-Piazuelo, Daniel;Amills, Marcel;Clop, Alex;Amills, Marcel;Clop, Alex;Karlskov-Mortensen, Peter;Fredholm, Merete;Li, Pinghua;Huang, Ruihua;Li, Pinghua;Huang, Ruihua;Tang, Guoqing;Li, Mingzhou;Liu, Xiaohong;Chen, Yaosheng;Zhang, Qin;Ding, Xiangdong;Fang, Lingzhao

    关键词：

微信小程序