文献类型： 外文期刊
第一作者： Xiao, Yuqing
作者： Xiao, Yuqing;Feng, Lei;Pan, Jiamin;Chen, Zeyu;Wang, Huiling;Yang, Shixing;Shen, Quan;Wang, Xiaochun;Zhang, Wen;Wang, Hao;Shan, Tongling
作者机构：
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
ISSN： 0304-8608
年卷期： 2020 年 165 卷 12 期
页码：
收录情况： SCI
摘要： Here, we investigated the fecal, oral, blood, and skin virome of 10 laboratory rabbits using a viral metagenomic method. In the oral samples, we detected a novel polyomavirus (RabPyV), and phylogenetic analysis based on the large T antigen, VP1 and VP2 regions indicated that the novel strain might have undergone a recombination event. Recombination analysis based on related genomes confirmed that RabPyV is a multiple recombinant between rodent-like and avian-like polyomaviruses. In fecal samples, three partial or complete genome sequences of viruses belonging to the familiesPicobirnaviridae,Parvoviridae,MicroviridaeandCoronaviridaewere characterized, and phylogenetic trees were constructed based on the predicted amino acid sequences of viral proteins. This study increases the amount of genetic information on viruses present in laboratory rabbits.
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