Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review

文献类型: 外文期刊

第一作者: Teame, Tsegay

作者: Teame, Tsegay;Gao, Chenchen;Zhou, Zhigang;Teame, Tsegay;Wang, Anran;Xie, Mingxu;Ding, Qianwen;Olsen, Rolf Erik;Zhang, Zhen;Yang, Yalin;Ran, Chao

作者机构:

关键词: paraprobiotics; postbiotics; Lactobacilli; metabolites; immunomodulatory effect

期刊名称:FRONTIERS IN NUTRITION ( 影响因子:6.576; )

ISSN: 2296-861X

年卷期: 2020 年 7 卷

页码:

收录情况: SCI

摘要: Lactobacilli comprise an important group of probiotics for both human and animals. The emerging concern regarding safety problems associated with live microbial cells is enhancing the interest in using cell components and metabolites derived from probiotic strains. Here, we define cell structural components and metabolites of probiotic bacteria as paraprobiotics and postbiotics, respectively. Paraprobiotics and postbiotics produced from Lactobacilli consist of a wide range of molecules including peptidoglycans, surface proteins, cell wall polysaccharides, secreted proteins, bacteriocins, and organic acids, which mediate positive effect on the host, such as immunomodulatory, anti-tumor, antimicrobial, and barrier-preservation effects. In this review, we systematically summarize the paraprobiotics and postbiotics derived from Lactobacilli and their beneficial functions. We also discuss the mechanisms underlying their beneficial effects on the host, and their interaction with the host cells. This review may boost our understanding on the benefits and molecular mechanisms associated with paraprobiotics and probiotics from Lactobacilli, which may promote their applications in humans and animals.

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