Efficient One-Step Synthesis of Lactide with High Yield and Selectivity Using Brønsted Acid Catalysis
文献类型： 外文期刊
第一作者： Qiu, Wenqi
作者： Qiu, Wenqi;Liu, Yukang;Zhang, Yufei;Wang, Xiaotao;Guo, Yuman;Liu, Hui;Guo, Zongxia;Zhao, Yingjie;Ouyang, Canbin
作者机构：
关键词： biodegradable polymers; Br & oslash;nsted acid catalysts; lactide syntheses; poly-lactic acid
期刊名称：CHEMSUSCHEM （ 影响因子：6.6； 五年影响因子：7.7 ）
ISSN： 1864-5631
年卷期： 2025 年 18 卷 13 期
页码：
收录情况： SCI
摘要： In this work, a one-step method synthesis of lactide is reported instead of the traditional two-step method. The selection of a suitable acid catalyst polyphosphoric acid and optimization of reaction conditions result in a yield of 97%. Moreover, this new one-step strategy eliminates the need for metal catalysts and does not require high-temperature conditions, thereby avoiding the issue of racemization. The simple one-step strategy offers a combination of efficiency, sustainability, and product quality improvements, making it a modern, practical approach to lactide synthesis.
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