Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review

文献类型： 外文期刊

第一作者： Sun, Jiaqiang

作者： Sun, Jiaqiang;Fu, Jing;He, Linlin;Guo, Xinmiao;Ye, Hua;Yin, Cuiyuan;Sun, Jiaqiang;Fu, Jing;He, Linlin;Sun, Jiaqiang;Fu, Jing;He, Linlin;Jiang, Yuelu;Li, Hongbo;Fu, Jing;Jiang, Heyuan

作者机构：

关键词： ultraviolet (UV); skin photoaging; epigallocatechin gallate (EGCG); beneficial effects

期刊名称：MOLECULES （ 影响因子：4.6； 五年影响因子：5.0 ）

ISSN：

年卷期： 2024 年 29 卷 22 期

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收录情况： SCI

摘要： Skin photoaging, primarily caused by ultraviolet (UV) radiation, leads to skin metabolic disorders, which have adverse psychological and physiological effects on individuals. However, traditional medications for repairing skin photoaging cause side effects. Natural bioactive compounds have been shown to prevent and treat skin photoaging with fewer side effects. Epigallocatechin gallate (EGCG), the main substance in tea polyphenols, is a natural bioactive compound with a range of properties. This review summarizes the beneficial effects and mechanisms of EGCG, as well as the application forms of EGCG in repairing photoaged skin. Results indicated that EGCG has repair effects, including improving elasticity, enhancing moisturization, inhibiting damage, and reducing pigmentation of photoaged skin. It has also been demonstrated that EGCG delivery systems, modified EGCG, and combinations with other bioactive substances could be used for repairing photoaged skin due to its poor stability and low bioavailability. EGCG effectively repairs various types of skin damage caused by UV radiation while maintaining normal skin structure and function. It is, therefore, an effective candidate for repairing photoaged skin. These results could provide references for the development and application of EGCG products for the treatment of photoaged skin.

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