Effect of site-specific heterogeneous evolution on phylogenetic reconstruction: A simple evaluation

文献类型： 外文期刊

第一作者： Su, Zhixi

作者： Su, Zhixi;Zhong, Yang;Gu, Xun;Su, Zhixi;Zhong, Yang;Gu, Xun;Cheng, Qiqun;Su, Zhixi;Gu, Xun;Cheng, Qiqun;Gu, Xun

作者机构：

关键词： DIVERGE;Heterogeneous evolution;Phylogenetic reconstruction

期刊名称：GENE （ 影响因子：3.688； 五年影响因子：3.329 ）

ISSN： 0378-1119

年卷期： 2009 年 441 卷 1-2 期

页码：

收录情况： SCI

摘要： Recent studies have shown that heterogeneous evolution may mislead phylogenetic analysis, which has been neglected for a long time. We evaluate the effect of heterogeneous evolution on phylogenetic analysis, using 18 fish mitogenomic coding sequences as an example. Using the software DIVERGE, we identify 198 amino acid sites that have experienced heterogeneous evolution. After removing these sites, the rest of sites are shown to be virtually homogeneous in the evolutionary rate. There are some differences between phylogenetic trees built with heterogeneous sites ("before tree") and without heterogeneous sites ("after tree"). Our study demonstrates that for phylogenetic reconstruction, an effective approach is to identify and remove sites with heterogeneous evolution, and suggests that researchers can use the software DIVERGE to remove the influence of heterogeneous evolution before reconstructing phylogenetic trees. (C) 2008 Elsevier B.V. All rights reserved.

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