Chromones from the Tobacco Derived Fungus Aspergillus versicolor and Their Antiviral Activity

文献类型： 外文期刊

第一作者： Shen, Si-Yu

作者： Shen, Si-Yu;Li, Shan-Shan;Liu, Xiao-Shan;Li, Yin-Ke;Miao, Dong;Wang, Wei-Guang;Du, Gang;Hu, Qiu-fen;Shen, Si-Yu;Li, Shan-Shan;Liu, Xiao-Shan;Gong, Da-Ping;Xiong, Wen;Li, Yin-Ke;Li, Xue-Mei;Ma, Xiao-Wei

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关键词： chromones; endophytic fungus Aspergillus versicolor; tobacco; anti-TMV activities

期刊名称：CHEMISTRY OF NATURAL COMPOUNDS （ 影响因子：0.8； 五年影响因子：0.8 ）

ISSN： 0009-3130

年卷期： 2023 年 59 卷 3 期

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收录情况： SCI

摘要： Two new chromones, 8-(3-hydroxypropyl)-2-(3-hydroxy-1-oxopropyl)-6-methoxy-4H-chromen-4-one (1), 2-acetyl-8-(3-hydroxypropyl)-6-methoxy-4H-chromen-4-one (2), along with four known ones (3-6) were isolated from the fermentation products of an endophytic fungus Aspergillus versicolor derived from tobacco. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1 and 2 exhibited potential anti-TMV activities with inhibition rates of 35.3 and 30.6%, respectively, rates that are close to that of positive control.

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