Two new dihydro-beta-agarofuran sesquiterpenes from the roots of Celastrus angulatus

文献类型: 外文期刊

第一作者: Tang, Juan

作者: Tang, Juan;Hu, Jia-Zhen;Chen, Yan-Ling;Zhao, Ting-Ting;Chen, Tao-Xiang;Hu, Cheng-Gang;Chen, Yan-Ling

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关键词: Celastraceae; Celastrus angulatus; dihydro-beta-agarofuran sesquiterpenes; single-crystal X-ray diffraction

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.61; 五年影响因子:1.591 )

ISSN: 1028-6020

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收录情况: SCI

摘要: Two new dihydro-beta-agarofuran sesquiterpenes chiapen T (1) and chiapen U (2), along with chiapen A (3), 1 beta-hydroxy-2 beta,6 alpha,12-triacetoxy-8 beta-(beta-nicotinoyloxy)-9 beta-(benzoyloxy)-beta-dihydroagarofuran (4), wilforlide B (5), 3-hydroxy-2-oxo-3-friedelen-29-oic acid (6), epikatonic acid (7), 22-epi-maytenfolic acid (8), maytenoic acid (9), wilforic acid F (10), wilforic acid B (11), were reported for the first time from the Celastrus angulatus. The structures of all the compounds were elucidated by HR-ESI-MS, 1 D and 2 D NMR spectra, as well as single-crystal X-ray diffraction analyses. Compounds 1 and 2 were examined for anti-inflammatory activity, respectively. None of them showed potent activity. [GRAPHICS] .

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