Effects of acute hypoxia stress on hemato-biochemical parameters, oxidative resistance ability, and immune responses of hybrid yellow catfish (Pelteobagrus fulvidraco x P. vachelli) juveniles

文献类型： 外文期刊

第一作者： Dagoudo, Missinhoun

作者： Dagoudo, Missinhoun;Qiang, Jun;Bao, Jin-Wen;Tao, Yi-Fan;Zhu, Tao Hao-Jun;Xu, Pao;Dagoudo, Missinhoun;Qiang, Jun;Tumukunde, Ezra Mutebi;Ngoepe, Tlou Kevin;Xu, Pao

作者机构：

关键词： Hybrid yellow catfish; Hypoxia stress; Metabolic response; Anaerobic metabolism; Mechanism

期刊名称：AQUACULTURE INTERNATIONAL （ 影响因子：2.235； 五年影响因子：2.616 ）

ISSN： 0967-6120

年卷期： 2021 年 29 卷 5 期

页码：

收录情况： SCI

摘要： Stress-induced by low water-dissolved oxygen (DO) negatively influences the overall fish performances. Hybrid yellow catfish (Pelteobagrus fulvidraco x P. vachelli) was subjected to 2 DO levels: 1.5 mg/L (hypoxia) and 6.5 mg/L (control-normoxia) during the period of the experiment. Blood and liver were sampled at 0.0-, 6.0-, 12.0-, 24.0-, 48.0-, and 96.0-h post-exposure. Results showed an increase in the hematological parameters including white blood cell (WBC), red blood cell (RBC), hemoglobin (HGB), and hematocrit percentage (HCT) during the first 24 h. HCT and HGB values were significantly increased after 6-h and 12-h post-exposure, whereas RBC and WBC counts were significantly decreased 48-h and 96-h post-exposure to hypoxia. Glucose, total cholesterol (TC), triglyceride (TG), alanine aminotransferase (ALT), and aspartate transaminase (AST) levels were increased in hypoxia group, meanwhile serum total protein (TP) showed balanced values in hypoxia group. Glucose values were significantly increased from 6 h, while the other parameters such ALT, AST, and TG were mostly significant increased at 96 h. Hypoxia-induced stress mostly affects the hepatic antioxidant and immune resistance functions, resulting in increments of cortisol levels, lysozyme, superoxide dismutase, and catalase enzyme activities. The concentration increments were observed in lactate dehydrogenase, hepatic TG, and complement C3 in hypoxia group. Liver TP and glycogen were reduced in the hypoxia group throughout the whole experiment time. Interestingly, all the indices (hemato-biochemical, oxidation, and immune resistance) were returned to normal after 96 h of recovery. Therefore, we conclude that DO below the normal threshold induced metabolic stress, immune suppression, and oxidative stress of the exposed fish. Although hybrid yellow catfish developed some strong adaptabilities to maintain oxygen provision, and generate energy from anaerobic sources to resist, these results contribute positively to the insights on different metabolic responses involved during hypoxic conditions.

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