农科机构知识库联盟

Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

文献类型：外文期刊

第一作者： Xu, Xun

作者： Xu, Xun;Li, Xin;Dong, Yang;Zhang, Guojie;Nielsen, Rasmus;Wang, Wen;Xu, Xun;Liu, Xin;Fang, Lin;Li, Jingxiang;He, Weiming;Zhang, Guojie;Li, Yingrui;Yu, Chang;Kristiansen, Karsten;Zhang, Xiuqing;Wang, Jian;Wang, Jun;Xu, Xun;Huang, Lei;Zheng, Xiaoming;Zhang, Fumin;Ge, Song;Huang, Lei;Zhang, Guojie;Zheng, Xiaoming;Jensen, Jeffrey D.;Hu, Fengyi;Gutenkunst, Ryan N.;He, Weiming;Kristiansen, Karsten;Nielsen, Rasmus;Wang, Jun;Wright, Mark;McCouch, Susan;Nielsen, Rasmus;Nielsen, Rasmus

作者机构：

期刊名称：NATURE BIOTECHNOLOGY （影响因子：54.908；五年影响因子：50.516 ）

ISSN： 1087-0156

年卷期： 2012 年 30 卷 1 期

页码：

收录情况： SCI

摘要： Rice is a staple crop that has undergone substantial phenotypic and physiological changes during domestication. Here we resequenced the genomes of 40 cultivated accessions selected from the major groups of rice and 10 accessions of their wild progenitors (Oryza rufipogon and Oryza nivara) to >15 x raw data coverage. We investigated genome-wide variation patterns in rice and obtained 6.5 million high-quality single nucleotide polymorphisms (SNPs) after excluding sites with missing data in any accession. Using these population SNP data, we identified thousands of genes with significantly lower diversity in cultivated but not wild rice, which represent candidate regions selected during domestication. Some of these variants are associated with important biological features, whereas others have yet to be functionally characterized. The molecular markers we have identified should be valuable for breeding and for identifying agronomically important genes in rice.

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