Fluorouracil implants caused a diaphragmatic tumor to be misdiagnosed as liver metastasis: a case report

文献类型： 外文期刊

第一作者： Shen, Yang-Yang

作者： Shen, Yang-Yang;Zhang, Jian-Bo;Wang, Zhen-Dan;Li, Pang;Zhang, Bo;Li, Sheng;Cui, Kai;Shen, Yang-Yang;Zhang, Jian-Bo;Wang, Zhen-Dan;Li, Pang;Zhang, Bo;Li, Sheng;Cui, Kai;Qin, Hong-Wei;Pang, Kai;Li, Sheng

作者机构：

关键词： Fluorouracil implants;Complication;Liver metastases;Raman spectroscopy;Sinofuan

期刊名称：BMC CANCER （ 影响因子：4.43； 五年影响因子：4.372 ）

ISSN： 1471-2407

年卷期： 2016 年 16 卷

页码：

收录情况： SCI

摘要： Background: Fluorouracil implants are widely used in peritoneal interstitial chemotherapy. Curative effects have been obtained, but implants have also caused some complications. Case presentation: We performed an analysis of a 66-year-old male patient's case history, as well as conventional pathological analysis and Raman spectroscopic detection of the diaphragmatic tumor. We also analyzed the underlying causes of this condition to prevent complications and reduce misdiagnoses in future cases. The patient had a history of peritoneal fluorouracil implantation. Pathological analysis of the diaphragmatic mass revealed foreign particles, and Raman detection showed that the mass contained fluorouracil. Conclusion: Fluorouracil implants may persist due to the high concentrations of this drug used in peritoneal chemotherapy. This finding should provide guidance and improve the application of peritoneal implants. In clinical trials, and the diagnosis of liver metastasis should be based on pathological results.

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