Molecular Characterization and Phylogenetic Analysis of New Variants of the Porcine Epidemic Diarrhea Virus in Gansu, China in 2012

文献类型： 外文期刊

第一作者： Tian, Yufei

作者： Tian, Yufei;Liu, Yuxiu;Yang, Zhenguo;Tian, Yufei;Yu, Zhijun;Huang, Jing;Xin, Yue;Li, Yuanguo;Wang, Tiecheng;Huang, Geng;Feng, Na;Yang, Songtao;Gao, Yuwei;Xia, Xianzhu;Yu, Zhijun;Fan, Shengtao;Yu, Zhijun;Fan, Shengtao;Cheng, Kaihui

作者机构：

关键词： molecular characterization;spike glycoprotein gene;phylogenetic analysis;porcine epidemic diarrhea virus (PEDV)

期刊名称：VIRUSES-BASEL （ 影响因子：5.048； 五年影响因子：5.127 ）

ISSN： 1999-4915

年卷期： 2013 年 5 卷 8 期

页码：

收录情况： SCI

摘要： Between January 2012 and March 2012, the infection rates of porcine epidemic diarrhea virus (PEDV) increased substantially in vaccinated swine herds in many porcine farms in Gansu Province, China. The spike (S) glycoprotein is an important determinant for PEDV biological properties. To determine the distribution profile of PEDV outbreak strains, we sequenced the full-length S gene of five samples from two farms where animals exhibited severe diarrhea and high mortality rates. Five new PEDV variants were identified, and the molecular diversity, phylogenetic relationships, and antigenicity analysis of Gansu field samples with other PEDV reference strains were investigated. A series of insertions, deletions, and mutations in the S gene was found in five PEDV variants compared with classical and vaccine strains. These mutations may provide stronger pathogenicity and antigenicity to the new PEDV variants that influenced the effectiveness of the CV777-based vaccine. Our results suggest that these new PEDV variant strains in Gansu Province might be from South Korean or South China, and the effectiveness of the CV777-based vaccine needs to be evaluated.

分类号：

  • 相关文献

[1]Further evidence for infection of pigs with human-like H1N1 influenza viruses in China. Yu, Hai,Zhou, Yan-Jun,Li, Guo-Xin,Yan, Li-Ping,Tong, Guang-Zhi,Zhang, Gui-Hong,Liao, Ming,Liu, Hui-Li. 2009

[2]Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) samples from field cases in Fujian, China. Chen, Xi,Yang, Jinxian,Yu, Fusong,Ge, Junqing,Lin, Tianlong,Song, Tieying. 2012

[3]Molecular characterization of new described kobuvirus in dogs with diarrhea in China. Kong, Ning,Zuo, Yewen,Wang, Zhongze,Yu, Hai,Shan, Tongling,Tong, Guangzhi,Kong, Ning,Yu, Hai,Shan, Tongling,Tong, Guangzhi,Kong, Ning,Zhou, En-min. 2016

[4]Identification of a peptide derived from the heptad repeat 2 region of the porcine epidemic diarrhea virus (PEDV) spike glycoprotein that is capable of suppressing PEDV entry and inducing neutralizing antibodies. Zhao, Pengwei,Wang, Ming,Zhao, Pengwei,Wang, Bin,Ji, Chun-Miao,Huang, Yao-Wei,Zhao, Pengwei,Wang, Bin,Ji, Chun-Miao,Huang, Yao-Wei,Cong, Xiaoyan. 2018

[5]Screening and identification of B cell antigenic Epitopes of porcine epidemic diarrhea virus spike glycoprotein by phage display. Sun Dong-Bo,Lang Hong-Wu,Shi Hong-Yan,Chen Jian-Fei,Cui Xiao-Chen,Wang Cheng-Bao,Tong You-En,Feng Li. 2007

[6]Coexistence of multiple genotypes of porcine epidemic diarrhea virus with novel mutant S genes in the Hubei Province of China in 2016. Zeng, Zhe,Peng, Gui-Qing,Li, Ting-Ting,Jin, Xin,Peng, Fu-Hu,Song, Nian-Hua,Ge, Xing-Yi. 2017

[7]Protein-DNA interactions in the promoter region of the gene encoding diapause hormone and pheromone biosynthesis activating neuropeptide of the cotton bollworm, Helicoverpa armigera. Hong, B,Zhang, ZF,Tang, SM,Yi, YZ,Zhang, TY,Xu, WH.

[8]Comprehensive molecular characterization of a transgenic pig expressing hCD46 gene. Wang, Qin,Liu, Xiaofei,Fu, Wei,Lin, Xiangmei,Shi, Ningning,Pan, Dengke,Shi, Ningning,Shang, Ying,Shang, Ying,Xu, Wentao,Zhao, Yiqiang.

[9]A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action. Zhang, Linbao,Yang, Dinglong,Wang, Qing,Wu, Huifeng,Pei, Dong,Cong, Ming,Li, Fei,Ji, Chenglong,Zhao, Jianmin,Zhang, Linbao,Yang, Dinglong,Wang, Qing,Wu, Huifeng,Pei, Dong,Cong, Ming,Li, Fei,Ji, Chenglong,Zhao, Jianmin,Zhang, Linbao,Yang, Dinglong,Yuan, Zeyi.

[10]Partial molecular characterization, expression pattern, polymorphism and association analysis of porcine SKP2 gene. Li, Y.,Zhao, S. H.,Peng, K. M.,Li, Y.,Yang, S. L.,Tang, Z. L.,Cui, W. T.,Mu, Y. L.,Chu, M. X.,Li, K.,Li, Y.,Wu, Z. F..

[11]Expression and SNP association analysis of porcine FBXL4 gene. Li, Y.,Yang, S. L.,Tang, Z. L.,Cui, W. T.,Mu, Y. L.,Chu, M. X.,Li, K.,Li, Y.,Li, Y.,Zhao, S. H.,Peng, K. M.,Wu, Z. F..

[12]Cloning and characterization of a cDNA clone encoding troponin T from tick Haemaphysalis qinghaiensis (Acari: Ixodidae). Gao, Jinliang,Luo, Jianxun,Fan, Ruiquan,Guan, Guiquan,Yin, Hong,Gao, Jinliang,Fingerle, Volker,Sugimoto, Chihiro,Inoue, Noboru.

[13]Detection and molecular characterization of recombinant avian leukosis viruses in commercial egg-type chickens in China. Liu, Chaonan,Wang, Yongqiang,Gao, Honglei,Gao, Yulong,Qi, Xiaole,Qin, Liting,Pan, Wei,Wang, Xiaomei,Zheng, Shimin,Jing, Long.

[14]Characterization of a Gallid herpesvirus 2 strain with novel reticuloendotheliosis virus long terminal repeat inserts. Zhang, Yan-ping,Bao, Ke-yan,Sun, Guo-rong,Lv, Hong-chao,Cui, Hong-yu,Gao, Yu-long,Wang, Xiao-mei,Liu, Chang-jun.

[15]Molecular characterization and expression pattern of three zona pellucida 3 genes in the Chinese sturgeon, Acipenser sinensis. Chuang-Ju, Li,Qi-Wei, Wei,Xi-Hua, Chen,Fang, Gan,Li, Zhou,Jian-Fang, Gui,Chuang-Ju, Li,Qi-Wei, Wei,Xi-Hua, Chen,Hong, Cao.

[16]The molecular characterization and RNAi silencing of SjZFP1 in Schistosoma japonicum. Liu, Xin,Liu, Jin-Ming,Song, Zhen-yu,Xing, Rong-He,Jin, Ya-Mei,Guo, Yan-hong,Li, Hao,Lu, Ke,Shi, Yao-jun,Cheng, Guo-feng,Lin, Jiao-Jiao,Lin, Jiao-Jiao.

[17]Isolation and Characterization of a Moderately Virulent Classical Swine Fever Virus Emerging in China. Luo, Y.,Ji, S.,Liu, Y.,Lei, J. -L.,Xia, S. -L.,Wang, Y.,Du, M. -L.,Shao, L.,Meng, X. -Y.,Zhou, M.,Sun, Y.,Qiu, H. -J.,Ji, S..

[18]Identification and tissue distribution of chemosensory protein and odorant binding protein genes in Athetis dissimilis (Lepidoptera: Noctuidae). Sun, Huizhong,Song, Yueqin,Wang, Xiaodong,Du, Jun,Cheng, Zhongji.

[19]Cloning and molecular characterization of phospholipase D (PLD) delta gene from longan (Dimocarpus longan Lour.). Zhang, Yayuan,Li, Li,Li, Zhichun,Li, Mingjuan,Li, Changbao,Sun, Jian,You, Xiangrong,Zhang, Yayuan,Li, Li,Li, Zhichun,Li, Mingjuan,Li, Changbao,Zhu, Jianhua,Peng, Hongxiang,Sun, Jian,Zhu, Jianhua,Peng, Hongxiang.

[20]Phenotypic and molecular characterization of rhizobacterium Burkholderia sp strain R456 antagonistic to Rhizoctonia solani, sheath blight of rice. Li, Bin,Liu, Bao-Ping,Lou, Miao-Miao,Xie, Guan-Lin,Li, Hong-Ye,Yu, Rong-Rong,Wang, Yan-Li,Sun, Guo-Chang.

作者其他论文 更多>>

微信小程序