Identification of BLAD and citrullinemia carriers in Chinese Holstein cattle

文献类型： 外文期刊

第一作者： Li, Jianbin

作者： Li, Jianbin;Zhang, Yi;Zhang, Yuan;Li, Jianbin;Wang, Hongmei;Hou, Minghai;Zhong, Jifeng

作者机构：

关键词： BLAD;citrullinemia;Chinese Holstein cattle;PCR-RFLP

期刊名称：ANIMAL SCIENCE PAPERS AND REPORTS （ 影响因子：1.078； 五年影响因子：1.097 ）

ISSN： 0860-4037

年卷期： 2011 年 29 卷 1 期

页码：

收录情况： SCI

摘要： Bovine leukocyte adhesion deficiency (BLAD) and citrullinemia are two autosomal recessive genetic diseases in Holstein cattle and both result in death of homozygous animals. Through the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technology and DNA sequencing, one citrullinemia and three BLAD carriers were found in a population of 615 Chinese Holstein cattle, including 436 cows and 179 bulls. Citrullinemia and BLAD carrier frequency was 0.16% and 0.49%, respectively, in tested Chinese Holstein cattle. In this study, the first citrullinemia carrier occurring in Chinese Holstein cattle is described, although the world frequency of this disorder is very low.

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