A simple method for the determination of enantiomeric composition of propranolol enantiomers

文献类型: 外文期刊

第一作者: Wei, Yanli

作者: Wei, Yanli;Kang, Hui;Ren, Yanfang;Shuang, Shaomin;Dong, Chuan;Qin, Guojie

作者机构:

期刊名称:ANALYST ( 影响因子:4.616; 五年影响因子:4.232 )

ISSN: 0003-2654

年卷期: 2013 年 138 卷 1 期

页码:

收录情况: SCI

摘要: A simple method of room temperature phosphorescence is proposed for the determination of propranolol enantiomeric composition based on beta-cyclodextrin as the chiral host and bromocyclohexane as the heavy atom. Enantiomeric complexes are formed upon binding of the propranolol enantiomer to beta-cyclodextrin, and the sign of the resultant phosphorescence signals allows for the identity of the propranolol enantiomers configuration to be determined successfully.

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