文献类型： 外文期刊
第一作者： Wei, Xin
作者： Wei, Xin;Chen, Mengjiao;Zhang, Qi;Liu, Jie;Yong, Kaicheng;Wang, Qin;Chen, Suhui;Hua, Hua;Luo, Zhaowei;Zhao, Xiaoyan;Wang, Xuan;Li, Wei;Cong, Jia;Yu, Xiting;Wang, Zhihan;Huang, Ruipeng;Chen, Jiaxin;Zhou, Xiaoyi;Qiu, Jie;Xu, Ping;Huang, Xuehui;Gong, Junyi;Fan, Jiongjiong;Murray, Jeremy;Han, Bin;Wang, Hai;Xu, Yang;Xu, Chenwu;Xu, Gen;Yang, Jinliang
作者机构：
期刊名称：SCIENCE （ 影响因子：45.8； 五年影响因子：49.7 ）
ISSN： 0036-8075
年卷期： 2024 年 385 卷 6704 期
页码：
收录情况： SCI
摘要： Understanding how numerous quantitative trait loci (QTL) shape phenotypic variation is an important question in genetics. To address this, we established a permanent population of 18,421 (18K) rice lines with reduced population structure. We generated reference-level genome assemblies of the founders and genotyped all 18K-rice lines through whole-genome sequencing. Through high-resolution mapping, 96 high-quality candidate genes contributing to variation in 16 traits were identified, including OsMADS22 and OsFTL1 verified as causal genes for panicle number and heading date, respectively. We identified epistatic QTL pairs and constructed a genetic interaction network with 19 genes serving as hubs. Overall, 170 masking epistasis pairs were characterized, serving as an important factor contributing to genetic background effects across diverse varieties. The work provides a basis to guide grain yield and quality improvements in rice.
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