Epidemiology and immunoprotection of nephropathogenic avian infectious bronchitis virus in southern China

文献类型： 外文期刊

第一作者： Xie, Qingmei

作者： Xie, Qingmei;Ji, Jun;Xie, Jingwei;Chen, Feng;Sun, Baoli;Ma, Jingyun;Bi, Yingzuo;Xie, Jingwei;Chen, Feng;Cai, Manshan;Xue, Chunyi

作者机构：

期刊名称：VIROLOGY JOURNAL （ 影响因子：4.099； 五年影响因子：3.719 ）

ISSN： 1743-422X

年卷期： 2011 年 8 卷

页码：

收录情况： SCI

摘要： Background: In last three years, 96 suspected poultry farms from different provinces in China were diagnosed for avian infectious bronchitis (IB) survey. Finally, 221 IBV strains were confirmed by dwarf embryo test and RT-PCR assay. By virus recovery trials, 187 of the isolates caused the birds died or distressed from nephritis, which was accordant with the clinical record. Results: Based on epidemiology analysis of recent field isolates of nephropathogenic IB in vaccinated farms in China, YL6 strain were used for vaccination and evaluated by antibody titer and challenge tests. The immunoprotection test indicated that the practical application of vaccine based on the recent field strains could finely facilitate controlling the nephropathogenic IB. Conclusions: Our study was aim at setting a guide for safeguard against nephropathogenic IBV-caused disease in China.

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