Sequence analysis of peste des petits ruminants virus from ibexes in Xinjiang, China

文献类型： 外文期刊

第一作者： Xia, J.

作者： Xia, J.;Wei, Y. R.;Ma, W. G.;Mi, X. Y.;Yi, Z.;Chen, S. J.;Du, W.;Duhaxi, C.;Han, T.;Huang, J.;Zheng, X. G.;Adili, G. Z.;Muhan, M.;Xue, X. M.;Gudai, B.

作者机构：

关键词： Peste des petits ruminants;Ibex;Xinjiang

期刊名称：GENETICS AND MOLECULAR RESEARCH （ 影响因子：0.764； 五年影响因子：0.912 ）

ISSN： 1676-5680

年卷期： 2016 年 15 卷 2 期

页码：

收录情况： SCI

摘要： Peste des petits ruminants (PPR) is an infectious disease caused by peste des petits ruminants virus (PPRV). While PPR mainly affects domestic goats and sheep, it also affects wild ungulates such as ibex, blue sheep, and gazelle, although there are few reports regarding PPRV infection in wild animals. Between January 2015 and February 2015, it was found for the first time that wild ibexes died from PPRV infection in Bazhou, Xinjiang, China, where a total of 38 ibexes (including young and adult ibexes) were found to have died abnormally from PPR-related issues. First, we tested for the presence of the F gene of PPRV by RT-PCR. Then, we compared the sequence of the isolated F gene from the ibex strain, termed PPRV Xinjiang/Ibex/2015, with those previously identified from small domestic ruminants from local areas near where the reported isolate was collected as well as those from other regions. The current sequence was phylogenetically classified as a lineage IV virus, and shared a high level of sequence identity (99.7%) with a previously described Xinjiang PPRV isolate.

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