The Polymorphism of a Mutation of IGF-1 Gene on Two Goat Breeds in China

文献类型: 外文期刊

第一作者: Wang Mou

作者: Wang Mou;Yu Hui;Huang Yong-Zhen;Xin Jing-Jing;Xin Ya-Ping;Chen Hong;Liu Wu-Jun;Fang Yi;Huang Xi-Xia;Yao Xin-Kui;Yu Shi-Gang;Fang Guang-Xin;Tian Ke-Chuan;Chen Hong

作者机构:

关键词: PCR-RFLP;IGF-1 gene;cashmere goat;cashmere traits;genotypes;China

期刊名称:JOURNAL OF ANIMAL AND VETERINARY ADVANCES ( 影响因子:0.365; 五年影响因子:0.359 )

ISSN: 1680-5593

年卷期: 2010 年 9 卷 4 期

页码:

收录情况: SCI

摘要: Searching for effects of candidate gene polymorphisms on cashmere production traits is an important goal for goat industry. Genetic variations in IGF-1 may alter protein function. This study investigated the association between polymorphisms in insulin-like growth factor-1 (IGF-1) and cashmere traits data with two Xinjiang local goat breeds. The results showed IGF-1-P1 locus has polymorphisms. The polymorphism locus of IGF-1-P1 by PCR-RFLP and DNA sequencing methods in 530 individuals from two Xinjiang local goat breeds in China. The frequencies of genotype AA in two goat breeds (Xinjiang goat, Nanjiang cashmere goat) were 0.487 and 0.277. Genotype BB was 0.274 and 0.486. Genotype AB was 0.239 and 0.236. The polymorphisms of the IGF-1 gene were associated with cashmere yield, fiber diameter, body weight in. cashmere goat. However, concern on cashmere production traits among three genotypes were shown not significantly (p>0.05).

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