The Role of Chitosan Oligosaccharide in Metabolic Syndrome: A Review of Possible Mechanisms

文献类型： 外文期刊

第一作者： Tao, Wenjing

作者： Tao, Wenjing;Wei, Jintao;Wang, Geng

作者机构：

关键词： chitosan oligosaccharide; metabolic syndrome; obesity; diabetes; hypertension

期刊名称：MARINE DRUGS （ 影响因子：5.118； 五年影响因子：5.951 ）

ISSN：

年卷期： 2021 年 19 卷 9 期

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收录情况： SCI

摘要： Metabolic syndrome, a cluster of metabolic disorders including central obesity, insulin resistance, hyperglycemia, dyslipidemia, and hypertension, has become a major public health problem worldwide. It is of great significance to develop natural products to prevent and treat metabolic syndrome. Chitosan oligosaccharide (COS) is an oligomer of chitosan prepared by the deacetylation of chitin, which is the second most abundant polymer in nature. In recent years, COS has received widespread attention due to its various biological activities. The present review will summarize the evidence from both in vitro and in vivo studies of the beneficial effects of COS on obesity, dyslipidemia, diabetes mellitus, hyperglycemia, and hypertension, and focus attention on possible mechanisms of the prevention and treatment of metabolic syndrome by COS.

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