Changes in the 3-dimensional distribution of mitochondria during meiotic divisions of mouse oocytes

文献类型： 外文期刊

第一作者： Li, CJ

作者： Li, CJ;Fan, BQ

作者机构：

关键词： mouse oocyte;meiotic maturation;parthenogenetic activation;mitochondrial redistribution;calcium changes

期刊名称：THERIOGENOLOGY （ 影响因子：2.74； 五年影响因子：2.93 ）

ISSN： 0093-691X

年卷期： 1997 年 48 卷 1 期

页码：

收录情况： SCI

摘要： Mitochondrial reorganization during meiotic maturation and parthenogenetic activation was studied in mouse oocytes using a laser scanning confocal microscope and a transmission electron microscope. Mitochondria were mainly distributed perinuclearly in the germinal vesicle (GV) stage oocytes and were dispersed throughout ooplasm after germinal vesicle breakdown (GVBD), except for a slightly higher occurrence in one hemisphere of oocytes, from which the first polar body (PbI) would become extruded. Mitochondria reaggregated around the metaphae II (MII), spindle and pronuclear region after alcohol activatation at the MII stage. The mitochondrial distribution may correspond to the Ca2+ changes during meiotic maturation and parthenogenetic activation. (C) 1997 by Elsevier Science Inc.

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