An ESIPT-Based Fluorescent Probe for Hydrazine Detection in Aqueous Solution and its Application in Living Cells

文献类型： 外文期刊

第一作者： Ju, Zhiyu

作者： Ju, Zhiyu;Li, Dapeng;Li, Dandan;Wu, Changzeng;Xu, Zhihong;Zhang, Di

作者机构：

关键词： Excited state intramolecular proton transfer;Fluorescence;Hydrazine;Biological imaging

期刊名称：JOURNAL OF FLUORESCENCE （ 影响因子：2.217； 五年影响因子：1.906 ）

ISSN： 1053-0509

年卷期： 2017 年 27 卷 2 期

页码：

收录情况： SCI

摘要： A new fluorescent probe based on "protection-deprotection" sequence and the excited-state intramolecular proton transfer (ESIPT) effect was designed and synthesized. The probe responds rapidly and high selectively toward hydrazine at room temperature, and exhibits a low detection limit of 0.016 mu M (0.512 ppb), which is well below the safety level (10 ppb) as regulated by EPA. Moreover, it can be applied for the imaging of hydrazine in living cells.

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