A Turn on ESIPT Probe for Rapid and Ratiometric Fluorogenic Detection of Hg2+ and its Application in Live-Cell Imaging

文献类型: 外文期刊

第一作者: Zhang, Di

作者: Zhang, Di;Liu, Jihong;Yin, Haiyan;Wang, Hongqi;Li, Shufang;Wang, Min;Li, Man;Zhou, Ling;Zhang, Junfeng;Zhang, Di;Liu, Jihong;Yin, Haiyan;Wang, Hongqi;Li, Shufang;Wang, Min;Li, Man;Zhou, Ling;Zhang, Junfeng;Zhang, Di;Liu, Jihong;Yin, Haiyan;Wang, Hongqi;Li, Shufang;Wang, Min;Li, Man;Zhou, Ling;Zhang, Junfeng

作者机构:

关键词: Hg2+;ESIPT;Thiophosphate;Fluorescence;Deprotection

期刊名称:JOURNAL OF FLUORESCENCE ( 影响因子:2.217; 五年影响因子:1.906 )

ISSN: 1053-0509

年卷期: 2016 年 26 卷 4 期

页码:

收录情况: SCI

摘要: A probe based on 2-(2'-hydroxyphenyl) benzothiazole (HBT) and thiophosphate has been synthesized and used for the ratiometric detection of Hg2+. The probe was designed in such a way that the excited state intramolecular proton transfer (ESIPT) of the HBT moiety get blocked. The probe exhibited a strong fluorescence enhancement upon addition of Hg2+ while showing almost no response to other cations in CH3CN/HEPES buffer solution. The probe exhibited fast selectivity towards Hg2+ and could be completed in 1 min. Fluorescence imaging experiments of Hg2+ in living TE-1 cells demonstrated its value of practical applications in biological systems.

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