The cellular receptors for infectious bursal disease virus

文献类型： 外文期刊

第一作者： Zhu, L. Q.

作者： Zhu, L. Q.;Wu, S. L.;Zhu, G. Q.;Zhang, G. P.

作者机构：

关键词： IBDV;SIgM;cellular receptor;chicken heat shock protein 90 alpha

期刊名称：AFRICAN JOURNAL OF BIOTECHNOLOGY （ 影响因子：0.573； 五年影响因子：0.794 ）

ISSN： 1684-5315

年卷期： 2008 年 7 卷 25 期

页码：

收录情况： SCI

摘要： Virus receptors are simplistically defined as cell surface molecules that mediate binding (attachment, adsorption) and/or trigger membrane fusion or entry through other processes. Infectious bursal disease virus (IBDV) entry into host cells occurs by recognition of specific cellular receptor(s) with viral envelope glycoprotein, which comprises the initial and key step of infection. Infection can be inhibited by blockage of the process. So the interest in receptors has been stimulated in large part by the potential in the application of developing substances that show directed blocking activity. While for the purpose one should know which host cell and viral molecules are involved in the reciprocal recognition and interaction leading to the virus entry into the cell. Here, the review presents the currently available knowledge regarding the receptors or molecules that interact with IBDV.

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