Cloning and characterization of porcine Fc gamma receptor II (FcR gamma II)

文献类型： 外文期刊

第一作者： Qiao, Songlin

作者： Qiao, Songlin;Zhang, Gaiping;Mac, Chun;Zhang, Hong;Zhang, Yuyang;Xi, Jun;Song, Haitao;Li, Xuewu

作者机构：

关键词： pig;Fc gamma RII;inhibitory receptor;rosetting

期刊名称：VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY （ 影响因子：2.046； 五年影响因子：2.217 ）

ISSN： 0165-2427

年卷期： 2006 年 114 卷 1-2 期

页码：

收录情况： SCI

摘要： Receptors for the Fc region (Fc gamma Rs) of IgG play a crucial role in the immune system and host protection against infection. In the present study, we describe the cloning, sequencing and characterization of porcine Fc gamma RII. By screening a translated EST database with the protein sequence of the human Fc gamma RII (CD32) we identified a putative porcine homologue. Using rapid amplification of cDNA ends (RACE), we isolated the full-length cDNA encoding porcine Fc gamma RII from peripheral blood leucocyte RNA. The porcine Fc gamma RII cDNA was 1488 bp long, encoding a 297 amino acid trans-membrane glycoprotein composed of two immunoglobulin-like extracelluar domains, a trans-membrane region and a cytoplasmic tail with an immunoreceptor tyrosine-based inhibitory motif (ITIM). The predicted amino acid sequence was found to be 67% and 52% identical with human and mouse Fc gamma RIIB. RT-PCR indicated porcine Fc gamma RII transcripts expressed in liver, alveolar, mesenteric lymph node and PBLs. COS-7 cells transfected with the pig Fc gamma RII cDNA were able to bind chicken erythrocytes sensitized with porcine IgG. Identification of porcine Fc gamma RII will aid in the understanding IgG-Fc gamma R interactions, and may help in developing new immunization protocols. (c) 2006 Elsevier B.V. All rights reserved.

分类号：

  • 相关文献

[1]Cloning and characterization of ovine immunoglobulin G Fc receptor II (Fc gamma RII). Liu, Yunchao,Qiao, Songlin,Zhang, Gaiping,Xi, Jun,You, Leiming,Tian, Xiaohui,Li, Qiaomu,Zhang, Lina,Guo, Junqing,Liu, Yunchao,Wang, Aiping. 2010

[2]Treating Cloned Embryos, But Not Donor Cells, with 5-aza-2 '-deoxycytidine Enhances the Developmental Competence of Porcine Cloned Embryos. Huan, Yan Jun,Zhu, Jiang,Xie, Bing Teng,Wang, Jian Yu,Liu, Shi Chao,Zhou, Yang,Kong, Qing Ran,Liu, Zhong Hua,Huan, Yan Jun,He, Hong Bin. 2013

[3]Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos. Huan, Yan Jun,Zhu, Jiang,Xie, Bing Teng,Wang, Jian Yu,Li, Jing Yu,Xue, Bing Hua,Kong, Qing Ran,Liu, Zhong Hua,Huan, Yan Jun,Wu, Zhan Feng,Zhang, Ji Guang.

[4]A genome-wide detection of copy number variations using SNP genotyping arrays in swine. Wang, Jiying,Jiang, Jicai,Fu, Weixuan,Jiang, Li,Ding, Xiangdong,Liu, Jian-Feng,Zhang, Qin,Wang, Jiying. 2012

[5]Single nucleotide polymorphism scanning and expression of the FRZB gene in pig populations. Wang, Zhixiu,Zhang, Bo,Yang, Yuzeng,Ban, Dongmei,Zhang, Hao,Li, Qinggang,Lu, Yunfeng. 2014

[6]Effects of Monoclonal Antibody Against Porcine 40-kDa Adipocyte-Specific Membrane Protein on Endocrine Secretion in Pigs. Zhao Su-mei,Zhang Xi,Duan Gang,Gao Shi-zheng,Hu Hong-mei,Liu Ling-yun. 2009

[7]Localization, Expression Change in PRRSV Infection and Association Analysis of the Porcine TAP1 Gene. Sun, Nunu,Liu, Dewu,Meng, Fanming,Zhang, Xianwei,Wu, Zhenfang,Sun, Nunu,Liu, Xiangdong,Xie, Shengsong,Li, Xinyun,Sun, Nunu,Liu, Xiangdong,Xie, Shengsong,Li, Xinyun,Chen, Hongbo,Chen, Huiyong. 2012

[8]Molecular cloning, sequence analysis, and function of the intestinal epithelial stem cell marker Bmi1 in pig intestinal epithelial cells. Li, C. -M.,Yan, H. -C.,Fu, H. -L.,Xu, G. -F.,Wang, X. -Q.. 2014

[9]Wnt antagonist, secreted frizzled-related protein 1, is involved in prenatal skeletal muscle development and is a target of miRNA-1/206 in pigs. Yang, Yalan,Sun, Wei,Wang, Ruiqi,Zhou, Rong,Tang, Zhonglin,Li, Kui,Yang, Yalan,Tang, Zhonglin,Li, Kui,Sun, Wei,Lei, Chuzhao. 2015

[10]Integrated analysis of mRNA and miRNA expression profiles in livers of Yimeng black pigs with extreme phenotypes for backfat thickness. Li, Wentong,Yang, Yalan,Zhou, Rong,Li, Kui,Li, Wentong,Liu, Shuai,Li, Xiuxiu,Wang, Yingping,Tang, Hui,Li, Wentong,Yang, Yalan,Liu, Ying,Zhang, Yanmin,Zhou, Rong,Li, Kui,Li, Kui. 2017

[11]Porcine LEM domain-containing 3: Molecular cloning, functional characterization, and polymorphism associated with ear size. Liang Jing,Li Na,Zhang Long-chao,Wang Li-gang,Liu Xin,Zhao Ka-bin,Yan Hua,Pu Lei,Zhang Yue-bo,Shi Hui-bi,Wang Li-xian,Li Na,Zhang Qin. 2016

[12]Identification and genetic effect of haplotypes in the promoter region of porcine myostatin gene. Liu, D.,Xu, Q.,Zang, L.,Liang, S.,Jiang, Y.,Wu, Y.,Wei, S.. 2011

[13]Single Nucleotide Polymorphism Scanning and Expression of the Pig PPARGC1A Gene in Different Breeds. Li, Qinggang,Lu, Yunfeng. 2014

[14]A novel pig gene, CPNE1, differentially expressed in the muscle tissues from Wujin pigs and Large White pigs. Liu Yonggang,Pu Shifei,Kong Chuisi. 2012

[15]A SOLUTION ON IDENTIFICATION AND REARING FILES IN SMALLHOLD PIG FARMING. Xiong, Benhai,Luo, Qingyao,Yang, Liang,Xiong, Benhai,Luo, Qingyao,Yang, Liang,Fu, Runting,Lin, Zhaohui. 2009

[16]Dynamic transcriptome and DNA methylome analyses on longissimus dorsi to identify genes underlying intramuscular fat content in pigs. Wang, Yuding,Ma, Cai,Sun, Yi,Kang, Li,Jiang, Yunliang,Wang, Yuding,Li, Yi. 2017

[17]Molecular cloning, expression and variation analyses of the dopamine D2 receptor gene in pig breeds in China. Xu, H. P.,He, X. M.,Hu, Y. S.,Jia, X. Z.,Nie, Q. H.,Zhang, X. Q.,Xu, H. P.,He, X. M.,Hu, Y. S.,Jia, X. Z.,Nie, Q. H.,Zhang, X. Q.,Fang, M. X.. 2011

[18]Selection of reference genes for studies of porcine endometrial gene expression on gestational day 12. Zhang, Hao. 2011

[19]Cloning, mapping and association study with carcass traits of the porcine SDHD gene. Zhu, ZM,Zhang, JB,Li, K,Zhao, SH. 2005

[20]Molecular characterization and expression pattern of the porcine STARS, a striated muscle-specific expressed gene. Peng, Y. B.,Guan, H. P.,Fan, B.,Zhao, S. H.,Xu, X. W.,Li, K.,Zhu, M. J.,Liu, B.,Li, K.,Yerle, M.. 2008

作者其他论文 更多>>

微信小程序