Genetic characterization of subtype H1 avian influenza viruses isolated from live poultry markets in Zhejiang Province, China, in 2011

文献类型： 外文期刊

第一作者： Wu, Hai-bo

作者： Wu, Hai-bo;Wu, Nan-ping;Wu, Hai-bo;Guo, Chao-tan;Wo, En-kang;You, Jin-biao;Wang, Yi-ting;Wang, Qiao-gang;Lu, Ru-feng;Xu, Li-hua

作者机构：

关键词： Avian influenza viruses;Subtype H1;Genetic analysis;Domestic ducks;Re-assortment

期刊名称：VIRUS GENES （ 影响因子：2.332； 五年影响因子：2.0 ）

ISSN： 0920-8569

年卷期： 2012 年 44 卷 3 期

页码：

收录情况： SCI

摘要： Nine avian influenza A viruses (AIVs), H1N2 (n = 2) and H1N3 (n = 7), were isolated from domestic ducks in live poultry markets in Zhejiang Province, Eastern China, in 2011. All viruses were characterized by whole genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that the viruses clustered in the Eurasian lineage of influenza A viruses. The hemagglutinin cleavage site of all viruses displayed features of a monobasic cleavage site. Although there was no evidence of re-assortment in subtype H1 AIVs among the avian species and mammalian hosts in this study, continued surveillance is needed considering the important role of the domestic duck in the dissemination and re-assortment of AIVs.

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