Effects of perilla extract on productive performance, serum values and hepatic expression of lipid-related genes in Shaoxing ducks
文献类型： 外文期刊
第一作者： Liu, W. M.
作者： Liu, W. M.;Shi, F. X.;Zhang, J.;Liu, W. M.;Zhang, J.;Lu, L. Z.;Tao, Z. R.;Shen, J. D.;Wang, D. Q.;Tian, Y.;Niu, D.;Wang, D. L.;Yu, B.
作者机构：
期刊名称：BRITISH POULTRY SCIENCE （ 影响因子：2.095； 五年影响因子：2.266 ）
ISSN： 0007-1668
年卷期： 2011 年 52 卷 3 期
页码：
收录情况： SCI
摘要： 1. The aim of this study was to identify the effect of perilla extract, a source of polyunsaturated fatty acids, on lipid metabolism and expression of lipid-related genes in livers of Shaoxing ducks. 2. Two hundred and forty 28-week-old laying ducks received a commercial diet with perilla extract added at 0 (control) or 200 mg/kg of feed. 3. Ducks fed on a diet with perilla extract had increased laying rates compared with control ducks. 4. Serum concentrations of triglycerides were reduced by perilla extract, while high-density lipoprotein cholesterol and total serum cholesterol increased. 5. The expression of genes involved in hepatic lipogenesis, sterol regulatory element-binding protein-1, acetyl CoA carboxylase, stearoyl CoA desaturase, fatty acid synthase, apolipoprotein B, and apolipoprotein very low density lipoprotein, were decreased in the perilla group. 6. The mRNA expression of peroxisome proliferators-activated receptor alpha and acyl-coenzyme A oxidase was enhanced following treatment with perilla extract, and a similar tendency was observed in the expression of liver fatty acid-binding protein. 7. The results show that a diet with 200 mg/kg perilla extract regulated fat metabolism of Shaoxing ducks by improving egg laying, altering serum lipid profiles, stimulating lipid catabolic gene expression and inibiting lipogenic gene expression in the liver.
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