Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects

文献类型: 外文期刊

第一作者: Liu, Xiaoyan

作者: Liu, Xiaoyan;Ruan, Lifang;Peng, Donghai;Li, Lin;Sun, Ming;Yu, Ziniu

作者机构:

关键词: thuringiensin;Bacillus thuringiensis;insecticidal mechanism;genetic determinants

期刊名称:TOXINS ( 影响因子:4.546; 五年影响因子:4.8 )

ISSN: 2072-6651

年卷期: 2014 年 6 卷 8 期

页码:

收录情况: SCI

摘要: Thuringiensin (Thu), also known as beta-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, and several nematode species. The chemical formula of Thu is C22H32O19N5P, and it is composed of adenosine, glucose, phosphoric acid, and gluconic diacid. In contrast to the more frequently studied insecticidal crystal protein, Thu is not a protein but a small molecule oligosaccharide. In this review, a detailed and updated description of the characteristics, structure, insecticidal mechanism, separation and purification technology, and genetic determinants of Thu is provided.

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