Associations of TCF12, CTNNAL1 and WNT10B gene polymorphisms with litter size in pigs

文献类型： 外文期刊

第一作者： Tao, Hu

作者： Tao, Hu;Sun, Xiaojie;Zhang, Xuying;Ma, Changping;Wang, Lei;Hua, Lun;Li, Fenge;Tao, Hu;Sun, Xiaojie;Zhang, Xuying;Ma, Changping;Wang, Lei;Hua, Lun;Li, Fenge;Mei, Shuqi;Peng, Xianwen

作者机构：

关键词： Pig;TCF12;CTNNAL1;WNT10B;Litter size;Single nucleotide polymorphism

期刊名称：ANIMAL REPRODUCTION SCIENCE （ 影响因子：2.145； 五年影响因子：2.281 ）

ISSN： 0378-4320

年卷期： 2013 年 140 卷 3-4 期

页码：

收录情况： SCI

摘要： In previous research, several WNT signaling pathway genes including transcription factor 12 (TCF12), catenin alpha-like protein 1 (CTNNAL1) and wingless-type MMTV integration site family, member 10B (WNT10B) were differentially expressed in PMSG-hCG stimulated preovulatory ovarian follicles of Large White and Chinese Taihu sows. In the present research, these three genes were selected as the candidate genes for litter size traits in pigs. Four mutations (TCF12 c.-201+65 G>A, TCF12 c.-200-300 G>A, CTNNAL1 c.1878 G>C and WNT10B c.*12 C>T) were detected in eleven pig populations, and results indicated CTNNAL1 c.1878 G and WNT10B c.12 C were the major alleles in all tested pig populations, while TCF12 c.-201+65 A and TCF12 c.-200-300 A were the major alleles in several Chinese native pig breeds. Association analysis of four mutations with litter size in Large White and DIV pigs showed that both the signficant differences of total number born (TNB) and number born alive (NBA) among three genotypes and the significance of additive effects appeared at TCF12 c.-200-300 G>A and CTNNAL1 c.1878 G>C loci, suggesting these two mutations might be reliable markers for pig selection and breeding. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved.

分类号：

  • 相关文献

[1]Erythropoietin Receptor Gene (EPOR) Polymorphisms are Associated with Sow Litter Sizes. Zhang Long-chao,Wang Li-gang,Li Yong,Yan Hua,Zhao Ke-bin,Wang Li-xian. 2011

[2]Identification of the promoter region and genetic mutations of the porcine GALP gene. Su, Lina,Tao, Hu,Sun, Xiaojie,Zhang, Xuying,Li, Fenge,Su, Lina,Tao, Hu,Sun, Xiaojie,Zhang, Xuying,Li, Fenge,Mei, Shuqi,Peng, Xianwen,Wu, Huayu,Qiao, Mu,Li, Fenge.

[3]Molecular cloning and polymorphism of the porcine H2AFZ gene. Zhang, Y. H.,Zuo, B.,Lei, M. G.,Xiong, Y. Z.,Li, F. E.,Zhang, Y. H.,Zuo, B.,Lei, M. G.,Xiong, Y. Z.,Li, F. E.,Mei, S. Q.,Peng, X. W.. 2009

[4]Effect of polymorphism in the leukemia inhibitory factor gene on litter size in Large White pigs. Lin, H. C.,Liu, G. F.,Wang, A. G.,Kong, L. J.,Wang, X. F.,Fu, J. L.,Lin, H. C.,Liu, G. F.,Wang, A. G.,Kong, L. J.,Wang, X. F.,Fu, J. L.,Lin, H. C..

[5]Transcription factor C/EBP beta and 17 beta-estradiol promote transcription of the porcine p53 gene. Tao, Hu,Zhang, Xuying,Yang, Jiahao,Zhu, Lihua,Zhou, Jiawei,Wang, Lei,Hua, Lun,Li, Fenge,Tao, Hu,Zhang, Xuying,Yang, Jiahao,Zhu, Lihua,Zhou, Jiawei,Wang, Lei,Hua, Lun,Li, Fenge,Mei, Shuqi,Peng, Xianwen,Wu, Huayu.

[6]Association of CYP19A1 gene polymorphisms with reproductive traits in pigs. Zhou Rong,Chen Jie,Li Kui,Zhou Rong,Yang Ya-lan,Liu Ying,Li Kui,Chen Qi-mei. 2017

[7]Heritabilities and genetic and phenotypic correlations of litter uniformity and litter size in Large White sows. Zhang Tian,Wang Li-gang,Shi Hui-bi,Yan Hua,Zhang Long-chao,Liu Xin,Pu Lei,Liang Jing,Zhang Yue-bo,Zhao Ke-bin,Wang Li-xian. 2016

[8]DNA Polymorphisms of 5 '-Flanking Region of Insulin-Like Growth Factor 1 Gene and Their Association with Reproduction Traits in Goats. Wang Ping-qing,Tan Ying,Zhang Bao-yun,Deng La-mei,Fan Qi,Liu Chong-xu,Chu Ming-xing. 2011

[9]DIFFERENTIAL EXPRESSION OF MIR-145, MIR-429 AND ITS TARGET GENES IN PARTIAL REPRODUCTIVE TISSUES OF SWINE WITH HIGH AND LOW LITTER SIZE. Zhang, Xiao-Dong,Feng, Yi-Fang,Zhang, Xu,Tian, Mi,Wu, Tao,Ye, Peng-Fei,Zhang, Wei,Ding, Yue-Yun,Yin, Zong-Jun,Zhang, Xiao-Dong,Feng, Yi-Fang,Zhang, Xu,Tian, Mi,Wu, Tao,Ye, Peng-Fei,Zhang, Wei,Ding, Yue-Yun,Yin, Zong-Jun,Chu, Ming-Xing. 2017

[10]Molecular cloning and expression pattern of the porcine 5-aminolevulinate synthase 1 (ALAS1) gene and its association with reproductive traits. Liu, L. Q.,Li, F. E.,Deng, C. Y.,Li, F. E.,Deng, C. Y.. 2016

[11]Polymorphism of bone morphogenetic protein 4 gene and its relationship with litter size of Jining Grey goats. Chu, M. X.,Feng, T.,Di, R.,Cao, G. L.,Fang, L.,Ma, Y. H.,Li, K.,Lu, L.,Wang, P. Q..

[12]Predictive potential of microsatellite markers on heterosis of fecundity in crossbred sheep. Di, R.,Chu, M. X.,Fang, L.,Feng, T.,Cao, G. L.,Li, Y. L.,Chen, H. Q.,Zhang, L.,Li, X. W..

[13]Polymorphism of GDF9 gene and its association with litter size in goats. Chu, M. X.,Feng, T.,Cao, G. L.,Fang, L.,Di, R.,Huang, D. W.,Wu, Z. H.,Li, X. W.,Li, N..

[14]Analysis on DNA sequence of KiSS-1 gene and its association with litter size in goats. Cao, G. L.,Chu, M. X.,Fang, L.,Di, R.,Feng, T.,Li, N..

[15]Polymorphism of 5' regulatory region of ovine FSHR gene and its association with litter size in Small Tail Han sheep. Chu, M. X.,Huang, D. W.,Feng, T.,Cao, G. L.,Fang, L.,Di, R.,Tang, Q. Q.,Ma, Y. H.,Li, K.,Guo, X. H.,Guo, X. H.,Feng, C. J.,Li, Y..

[16]Association between PCR-SSCP of bone morphogenetic protein 15 gene and prolificacy in Jining Grey goats. Chu, M. X.,Jiao, C. L.,He, Y. Q.,Wang, J. Y.,Liu, Z. H.,Chen, G. H..

[17]Analysis on DNA sequence of goat RFRP gene and its possible association with average daily sunshine duration. Huang, D. W.,Di, R.,Wang, J. X.,Chu, M. X.,He, J. N.,Cao, G. L.,Fang, L.,Feng, T.,Li, N..

[18]Polymorphisms of caprine GDF9 gene and their association with litter size in Jining Grey goats. Feng, T.,Chu, M. X.,Cao, G. L.,Di, R.,Fang, L.,Geng, C. X.,Chen, H. Q.,Lang, X. Z.,Liu, X. L.,Li, N..

[19]Prolactin receptor as a candidate gene for prolificacy of small tail han sheep. Chu, M. X.,Mu, Y. L.,Fang, L.,Ye, S. C.,Sun, S. H..

[20]Association between polymorphism of GPR54 gene and litter size in Small Tail Han sheep. Tang, Q. Q.,Chu, M. X.,Cao, G. L.,Fang, L.,Di, R.,Feng, T.,Huang, D. W.,Li, N.. 2012

作者其他论文 更多>>

微信小程序