Spliceosomal protein U1A is involved in alternative splicing and salt stress tolerance in Arabidopsis thaliana

文献类型： 外文期刊

第一作者： Gu, Jinbao

作者： Gu, Jinbao;Luo, Yuehua;Jiang, Xingyu;Wang, Zhen-Yu;Xia, Zhiqiang;Qian, Bilian;Zhu, Jianhua;Xie, He;Zhu, Jian-Kang;Zhu, Jian-Kang;Xiong, Liming

作者机构：

期刊名称：NUCLEIC ACIDS RESEARCH （ 影响因子：16.971； 五年影响因子：15.542 ）

ISSN： 0305-1048

年卷期： 2018 年 46 卷 4 期

页码：

收录情况： SCI

摘要： Soil salinity is a significant threat to sustainable agricultural production worldwide. Plants must adjust their developmental and physiological processes to cope with salt stress. Although the capacity for adaptation ultimately depends on the genome, the exceptional versatility in gene regulation provided by the spliceosome-mediated alternative splicing (AS) is essential in these adaptive processes. However, the functions of the spliceosome in plant stress responses are poorly understood. Here, we report the in-depth characterization of a U1 spliceosomal protein, AtU1A, in controlling AS of pre-mRNAs under salt stress and salt stress tolerance in Arabidopsis thaliana. The atu1a mutant was hypersensitive to salt stress and accumulated more reactive oxygen species (ROS) than the wild-type under salt stress. RNA-seq analysis revealed that AtU1A regulates AS of many genes, presumably through modulating recognition of 5' splice sites. We showed that AtU1A is associated with the pre-mRNA of the ROS detoxification-related gene ACO1 and is necessary for the regulation of ACO1 AS. ACO1 is important for salt tolerance because ectopic expression of ACO1 in the atu1a mutant can partially rescue its salt hypersensitive phenotype. Our findings highlight the critical role of AtU1A as a regulator of pre-mRNA processing and salt tolerance in plants.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Epigenetics in the modern era of crop improvements

    作者：Xue, Yan;Deng, Xing Wang;Cao, Xiaofeng;Deng, Xian;Cao, Xiaofeng;Deng, Xian;Chen, Xiangsong;Yang, Hongchun;Ding, Yong;Dong, Aiwu;Liu, Bing;Ren, Guodong;Zhang, Yijing;Duan, Cheng-Guo;Fang, Xiaofeng;Qi, Yijun;Gong, Lei;Liu, Bao;Xu, Zheng-Yi;Gong, Zhizhong;Gong, Zhizhong;Gu, Xiaofeng;He, Chongsheng;He, Hang;He, Shengbo;He, Xin-Jian;He, Yan;Tian, Zhixi;He, Yuehui;Jia, Guifang;Wang, Yuan;Jiang, Danhua;Song, Xianwei;Jiang, Jianjun;Lai, Jinsheng;Lai, Jinsheng;Lai, Jinsheng;Lai, Jinsheng;Lai, Jinsheng;Lang, Zhaobo;Zhu, Jian-Kang;Li, Chenlong;Li, Qing;Li, Xingwang;Yan, Wenhao;Zhou, Dao-Xiu;Luo, Xiao;Qian, Weiqiang;Song, Qingxin;Wang, Jia-Wei;Xu, Lin;Wu, Liang;Wu, Zhe;Xia, Rui;Xiao, Jun;Zhao, Yusheng;Zhai, Jixian;Zhong, Xuehua;Zhou, Dao-Xiu;Zhou, Ming;Zhou, Yue;Zhu, Bo;Liu, Qikun

    关键词：epigenetics; plant development; plant immunity; crop improvement; stress responses

  • Identifying resistant mutations in the herbicide target site of the plant 4-hydroxyphenylpyruvate dioxygenase

    作者：Wang, Mugui;Xue, Li;Zhu, Jian-Kang;Wang, Mugui;Xue, Li;Zhu, Jian-Kang;Wang, Mugui;Zhong, Yingli;He, Yuxin;Xie, Jiyong;Wang, Yingying;Zinta, Gaurav;Verma, Vipasha;Wang, Hongzhi;Mao, Yanfei;Wang, Mugui;Zhong, Yingli;He, Yuxin;Xie, Jiyong;Wang, Yingying;Zinta, Gaurav;Verma, Vipasha;Wang, Hongzhi;Mao, Yanfei;Zhong, Yingli;He, Yuxin;Xie, Jiyong;Wang, Yingying;Wang, Hongzhi;Xie, Hongtao;Wang, Xin;Zhu, Jian-Kang;Zhu, Jian-Kang

    关键词：herbicide-resistant; HPPD; base editing; target-site-resistance; artificial gene evolve

  • Emergence of ciprofloxacin-and tigecycline-resistant extended-spectrum β-lactamase (ESBL)-producing Salmonella enterica serovar Kentucky ST198 from horse, China

    作者：Zhang, Xing-Xing;Huang, Xin;Li, Xue-Qin;Li, Qiuchun;Zhong, Fa-Gang;Zhang, Xing-Xing;Wang, Zhen-Yu;Jiang, Yue;Jiao, Xinan;Li, Qiuchun;Wang, Jing

    关键词：CTX-M; Salmonella enterica serovar Kentucky; ST198; Extensively drug-resistant horse

  • Integration of metabolic and transcriptomic analyses for revealing the galactose metabolism of tobacco (Nicotiana tabacum) under salt stress

    作者：Bai, Ge;Li, Yong;Yang, Da-Hai;Fei, Mingliang;Pang, Tao;Xie, He;Bai, Ge;Zhang, Hui;Fu, Yaning;Zhang, Hui;Yang, Ai-Guo;Wang, Zhen-Yu;Gu, Jinbao

    关键词：salt stress; metabolomics; transcriptomics; tobacco plants; molecular mechanisms; salt tolerance

  • Targeted deaminase-free T-to-G and C-to-K base editing in rice by fused human uracil DNA glycosylase variants

    作者：Wu, Yinghuang;Wang, Xueying;Wang, Haoyu;Han, Ying;Wang, Yaxuan;Zou, Chunyu;Zhu, Jian-Kang;Li, Ming;Wu, Yinghuang;Wang, Xueying;Wang, Haoyu;Han, Ying;Wang, Yaxuan;Zou, Chunyu;Zhu, Jian-Kang;Li, Ming;Zhu, Jian-Kang;Zhu, Jian-Kang

    关键词：Base Editor; nCas9; pCKBE; pTGBE; UNG

  • Pan-genome and haplotype map of cassava cultivars and wild ancestors provide insights into its adaptive evolution and domestication

    作者：Xia, Zhiqiang;Zhou, Xincheng;Jiang, Sirong;Chen, Fei;Zou, Meiling;Xu, Liangye;Guo, Xin;Wang, Shujuan;Li, Mengtao;Liu, Shisheng;Bao, Yuting;Zhang, Chenji;Xiao, Jianjia;Guo, Fengguang;Shen, Xu;Li, Haozheng;Zhang, Huaifang;He, Shuang;Wan, Yinglang;Chen, Yinhua;Huang, Dongyi;Li, Bin;Peng, Ming;Chen, Xin;Wang, Wenquan;Du, Zhenglin;Chen, Meili;Zhao, Wenming;Xiao, Jingfa;Du, Zhenglin;Chen, Meili;Zhao, Wenming;Xiao, Jingfa;Zhou, Xincheng;Wang, Haiyan;Lu, Cheng;Peng, Ming;Chen, Xin;Zhu, Tingting;Wang, Le;Luo, Ming-Cheng;Qiao, Fei;Li, Kaimian;Carvalho, Luiz;Lopez-Lavalle, Luis Augusto Becerra;Zhang, Xiaofei;Ceballos, Hernan;Wang, Zhenyu;Li, Yuanchao;Zhao, Long;Yan, Huabing;Qin, Xiaochun;Ma, Ling;Zhang, Weixiong;Moller, Birger Lindberg

    关键词：genome; pan-genome; structural variations; selective sweeping; evolution and domestication; cassava

  • Genetic Diversity and Population Structural Analysis of Areca catechu Revealed by Single-Nucleotide Polymorphism Markers

    作者：Qi, Lan;Zhou, Huanqi;Liu, Fan;Mehmood, Sajid;Huang, Liyun;He, Miaohua;Jiang, Sirong;Xia, Zhiqiang;Mehmood, Sajid

    关键词：Areca catechu L.; germplasm resources; SNPs; genetic diversity; population structure

微信小程序