Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer

文献类型： 外文期刊

第一作者： Yang, Ningning

作者： Yang, Ningning;Ma, Qingyun;Huang, Shengzhuo;Dai, Haofu;Guo, Zhikai;Lu, Xuehua;Wang, Yuguang;Zhao, Youxing;Yang, Ningning;Yu, Zhifang

作者机构：

关键词： Marasmiellus ramealis (Bull.) Singer;eudesmane;sesquiterpenoids;mellein;AChE inhibition

期刊名称：JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY （ 影响因子：1.838； 五年影响因子：1.9 ）

ISSN： 0103-5053

年卷期： 2015 年 26 卷 1 期

页码：

收录情况： SCI

摘要： Chemical investigation on the cultures of the fungus Marasmiellus ramealis resulted in the first isolation of eleven compounds including two new eudesmane-type sesquiterpenoids 14(10 -> 1)abeo-eudesmane-13-hydroxyl-11-ene, 14(10 -> 1)abeo-eudesmane-11,13-diol, and the new mellein derivative (R)-(-)-5-ethoxycarbonyl mellein. The first two compounds were evaluated for their inhibitory activity against acetylcholinesterase (AChE), and proved to be active with a percentage inhibition of 29 and 41%, respectively, at a concentration of 100 mu mol L-1.

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