Azalomycin F-4a 2-ethylpentyl ester, a new macrocyclic lactone, from mangrove actinomycete Streptomyces sp 211726

文献类型: 外文期刊

第一作者: Yuan, Gan Jun

作者: Yuan, Gan Jun;Hong, Kui;Lin, Hai Peng;Yuan, Gan Jun;Li, Jia

作者机构:

关键词: Streptomyces sp 211726;Azalomycin F-4a 2-ethylpentyl ester;Antifungal activity;Cytotoxity

期刊名称:CHINESE CHEMICAL LETTERS ( 影响因子:6.779; 五年影响因子:4.558 )

ISSN: 1001-8417

年卷期: 2010 年 21 卷 8 期

页码:

收录情况: SCI

摘要: Azalomycin F-4a 2-ethylpentyl ester, a new 36-membered macrocyclic lactone antibiotic, was isolated from mangrove actinomycete Streptomyces sp. 211726. Its structure was elucidated on the basis of spectroscopic data. The compound showed broad-spectrum antifungal activity and moderate cytotoxicity against human colon tumor cell HCT-116. (C) 2010 Kui Hong. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

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