Effects of dissolved oxygen on intestinal bacterial community and immunity of Atlantic salmon Salmo salar

文献类型： 外文期刊

第一作者： Xu, Shihong

作者： Xu, Shihong;Babu, V. Sarath;Lin, Li;Chi, Liang;Gao, Caixia;Xu, Shihong;Wang, Yanfeng;Li, Jun;Liu, Qinghua;Xiao, Zhizhong;Babu, V. Sarath;Lin, Li;Xu, Yingxuan;Zhao, Chunyan

作者机构：

关键词： Atlantic salmon; dissolved oxygen (DO); immune responses; microbiota; intestine

期刊名称：JOURNAL OF OCEANOLOGY AND LIMNOLOGY （ 影响因子：1.6； 五年影响因子：1.6 ）

ISSN： 2096-5508

年卷期： 2023 年 41 卷 1 期

页码：

收录情况： SCI

摘要： Dissolved oxygen (DO) is one of most important factors which affect wide range physiologic features of fish, including immune responses and intestinal bacterial community. However, the underlying mechanisms remain enigmatic. To address this question, the intestinal bacterial community compositions and the immune features of Atlantic salmon (Salmo salar) grown in recirculating aquaculture systems (RAS) were characterized. Fish were reared under different DO saturation levels, e.g., 200% saturation named high group (H), 100% saturation named control group (CK), and 60% saturation named lower group (L). Large variations in the operational taxonomic units (OTUs) frequency distribution for the intestinal bacterial community of Atlantic salmon were observed. The intestinal bacterial community of all groups was dominated mainly by three phyla, e.g., Proteobacteria, Firmicutes, and Bacteroidetes. Interestingly, Acinetobacter baumannii, an opportunistic pathogen of salmon was increased significantly in L group. We further monitored the immunity features of fish under different DO levels. The results show that leucocyte number, cortisol level, the expressions of interleukin-1 beta (IL-1 beta), Toll-like receptor 4 (TLR4), and nucleotide-binding oligomerization domain like protein 2 (NOD2) were higher at significant levels in the L group than those in the other two groups. TLR4 and NOD2 are usually related with the bacterial infections; therefore, it is reasonable to believe that the stronger immune responses observed in the L group might be related with the higher abundance of A. baumannii in the intestine of Atlantic salmon. Overall, these findings demonstrated that low DO level may induce stronger immunity responses in Atlantic salmon.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序