CRISPR-Cas: a game-changer in vaccine development and the fight against viral infections

文献类型： 外文期刊

第一作者： Yang, Fayu

作者： Yang, Fayu;Zhu, Zixiang;Zheng, Haixue;Zhang, Shilei;Yang, Fayu;Zhu, Zixiang;Zheng, Haixue;Zhang, Shilei;Aliyari, Saba;Cheng, Genhong

作者机构：

期刊名称：TRENDS IN MICROBIOLOGY （ 影响因子：14.9； 五年影响因子：16.9 ）

ISSN： 0966-842X

年卷期： 2025 年 33 卷 6 期

页码：

收录情况： SCI

摘要： Understanding the mechanisms of virus-host interactions is crucial for advancing our knowledge of viral pathogenesis and developing effective antiviral strategies. As novel, highly virulent pathogens continue to emerge, overcoming the challenges in virus-host biology and infection control is more important than ever. The CRISPR-Cas system has revolutionized genetic engineering, offering a precise and efficient application in synthetic biology. It is also invaluable in virology research, diagnostics, and antiviral therapeutics. In this review, we explore the latest advances in CRISPR-Cas-based approaches to elucidate virus-host interactions, focusing on the identification of key receptors and host factors essential for virus infection. Furthermore, we discuss the potential of the CRISPR-Cas system as an antiviral strategy for tackling newly emerging and re-emerging viruses. Finally, we discuss the potential of CRISPR-Cas-based gene editing for the development of innovative viral vaccines.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序