The Main Anthocyanin Monomer from Lycium ruthenicum Murray Fruit Mediates Obesity via Modulating the Gut Microbiota and Improving the Intestinal Barrier
文献类型： 外文期刊
第一作者： Liu, Peiyun
作者： Liu, Peiyun;Zhou, Wangting;Xu, Weiqi;Peng, Yujia;Zeng, Xiaoxiong;Yan, Yamei;Lu, Lu;Mi, Jia;Cao, Youlong;Yan, Yamei;Lu, Lu;Mi, Jia;Cao, Youlong
作者机构：
关键词： Lycium ruthenicum Murray; anthocyanins; obesity; gut microbiota; intestinal barrier
期刊名称：FOODS （ 影响因子：5.561； 五年影响因子：5.94 ）
ISSN：
年卷期： 2022 年 11 卷 1 期
页码：
收录情况： SCI
摘要： Anthocyanins have been shown to exert certain antiobesity properties, but the specific relationship between anthocyanin-induced beneficial effects and the gut microbiota remains unclear. Petunidin-3-O-[rhamnopyranosyl-(trans-p-coumaroyl)]-5-O-(beta-D-glucopyranoside) (P3G) is the main anthocyanin monomer from the fruit of Lycium ruthenicum Murray. Therefore, in this study, we investigated the antiobesity and remodeling effects of P3G on gut microbiota through a high-fat diet (HFD)-induced obesity mouse model and a fecal microbiota transplantation experiment. P3G was found to reduce body weight gain, fat accumulation, and liver steatosis in HFD-induced obese mice. Moreover, supplementation with P3G alleviated the HFD-induced imbalance in gut microbiota composition, and transferring the P3G-regulated gut microbiota to recipient mice provided comparable protection against obesity. This is the first time evidence is provided that P3G has an antiobesity effect by changing the intestinal microbiota. Our present data highlight a link between P3G intervention and enhancement in gut barrier integrity. This may be a promising option for obesity prevention.
分类号：
- 相关文献
作者其他论文 更多>>
-
Color and Nutritional Analysis of Ten Different Purple Sweet Potato Varieties Cultivated in China via Principal Component Analysis and Cluster Analysis
作者：Xu, Meng;Li, Jia;Yin, Jinjing;Wu, Muci;Zhou, Wangting;Zhang, Rui;He, Jingren;Yang, Xinsun;He, Jingren
关键词：purple sweet potatoes; nutritional components; anthocyanin composition; principal component analysis; cluster analysis
-
In vivo absorption and fecal excretion of polysaccharides from the fruits of Lycium barbarum L. in rats through fluorescence labeling
作者：Zhou, Wangting;Kan, Xuhui;Dong, Wei;Sun, Yi;Zeng, Xiaoxiong;Yan, Yamei;Mi, Jia;Lu, Lu;Cao, Youlong;Wang, Wei
关键词：Lycium barbarum polysaccharides; Fluorescence labeling; Absorption
-
Anthocyanins from Lycium ruthenicum Murray Prevent High-Fat Diet-Induced Obesity in Female Mice via Gut Microbiota-Related Bile Acids Metabolism
作者：Li, Hui;Zhang, Meng;Tan, Tingting;Li, Shiying;Ran, Linwu;Li, Hui;Zhang, Meng;Tan, Tingting;Li, Shiying;Ran, Linwu;Mi, Jia;Lu, Lu;Yan, Yamei
关键词：Lycium ruthenicum Murray; female obesity; gut microbiota; bile acid metabolism
-
Petunidin-3-O-[rhamnopyranosyl-(trans-p-coumaroyl)]-5-O-(β-D-glucopyranoside), the main anthocyanin from the fruits of Lycium ruthenicum murray, enhances the lifespan of Caenorhabditis elegans by activating DAF-16 and improving the gut microbiota
作者：Zhang, Kangzhi;Zhu, Jiahao;Liu, Peiyun;Guo, Renpeng;Zeng, Xiaoxiong;Yan, Yamei;Mi, Jia;Lu, Lu;Cao, Youlong;Yan, Yamei;Mi, Jia;Lu, Lu;Cao, Youlong
关键词：Lycium ruthenicum murray; Caenorhabditis elegans; Lifespan; Antioxidant; Resistance; DAF-16; Intestinal microbiota
-
Effects of Storage Temperatures and Times on Drying Chicken Breasts Using Film-Drying: A New Application of Polymeric Film for Food Preservation
作者：Alnadari, Fawze;Sallam, Abubakr;Abdalmegeed, Dyaaaldin;Zeng, Xiaoxiong;Alnadari, Fawze;Alnadari, Fawze;Al-Dalali, Sam;Nasiru, Mustapha Muhammad;Korma, Sameh A.;Abdin, Mohamed;Baiome, Baiome Abdelmaguid;Chen, Chao
关键词：antimicrobial; dehydration film; food quality monitoring; freshness preservation; lipid oxidation; rehydration
-
In vivo absorption and excretion in rats and in vitro digestion and fermentation by the human intestinal microbiota of 2-O-β-
d -glucopyranosyl-l -ascorbic acid from the fruits of Lycium barbarum L作者：Dong, Wei;Peng, Yujia;Xu, Weiqi;Zhou, Wangting;Zeng, Xiaoxiong;Yan, Yamei;Mi, Jia;Lu, Lu;Cao, Youlong;Yan, Yamei;Mi, Jia;Lu, Lu;Cao, Youlong
关键词：
-
The polysaccharides from the fruits of Lycium barbarum ameliorate high-fat and high-fructose diet-induced cognitive impairment via regulating blood glucose and mediating gut microbiota
作者：Tian, Xinyi;Dong, Wei;Zhou, Wangting;Sun, Yi;Zeng, Xiaoxiong;Yan, Yamei;Lu, Lu;Mi, Jia;Cao, Youlong;Yan, Yamei;Lu, Lu;Mi, Jia;Cao, Youlong
关键词：Polysaccharides; Neuroinflammation; Blood glucose homeostasis; Gut microbiota; Short-chain fatty acids
