Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid
文献类型： 外文期刊
作者： Zhu, Yu-Jing 1 ; Zhou, Han-Tao 2 ; Hu, Yong-Hua 2 ; Tang, Jian-Yang 1 ; Su, Ming-Xing 1 ; Guo, Yun-Ji 2 ; Chen, Qing-X 1 ;
作者机构： 1.Fujian Acad Agr Sci, Agr Bioresources Inst, Fuzhou 350003, Peoples R China
2.Xiamen Univ, Sch Life Sci, Key Lab, Minist Educ Coastal & Wetland Ecosyst, Xiamen 361005, Peoples R China
3.Xiamen Univ, Key Lab Chem Biol Fujian Prov, Xiamen, Peoples R China
关键词： 2-phenylethanol;2-phenylacetaldehyde;2-phenylacetic acid;antityrosinase activity;antimicrobial activity
期刊名称：FOOD CHEMISTRY （ 影响因子：7.514； 五年影响因子：7.516 ）
ISSN：
年卷期：
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收录情况： SCI
摘要： The inhibition kinetics of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid on the enzyme activity of mushroom tyrosinase have been investigated. The results showed that these aromatic compounds can lead to reversible inhibition of the enzyme; furthermore, 2-phenylacetaldehyde and 2-phenylacetic acid are uncompetitive inhibitors and 2-phenylethanol is a mixed-type inhibitor. The inhibition constants have been determined and the inhibiting ability was: 2-phenylacetaldehyde > 2-phenylacetic acid > 2-phenylethanol, indicating that the functional group on the benzene ring group played an important role in the inhibition of the enzyme. In addition, 2-phenylacetic acid and 2-phenylethanol were found to have effective antibacterial activities, and 2-phenylacetic acid was more effective against Esch-erichia coli and Ralstonia solanacearum than 2-phenylethanol, but 2-phenylacetaldehyde lacked of antibacterial activity.
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