您好，欢迎访问浙江省农业科学院 机构知识库！
浙江省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Stereoselective determination of famoxadone enantiomers with HPLC-MS/MS and evaluation of their dissipation process in spinach

文献类型： 外文期刊

作者： Qian, Mingrong 1 ; Wu, Liqin 1 ; Zhang, Hu 1 ; Wang, Jingwen 2 ; Li, Rui 1 ; Wang, Xiangyun 1 ; Chen, Zhimin 1 ;

作者机构： 1.Zhejiang Acad Agr Sci, Inst Qual & Standard Agr Prod, Hangzhou, Zhejiang, Peoples R China

2.Hangzhou Plant Protect & Soil Fertilizer Stn, Hangzhou, Zhejiang, Peoples R China

关键词： Enantioselectivity;Famoxadone;HPLC-MS/MS/dissipation

期刊名称：JOURNAL OF SEPARATION SCIENCE （ 影响因子：3.645； 五年影响因子：2.943 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： A simple and enantioselective method for the determination of famoxadone enantiomers in spinach using reversed-phase HPLC-MS/MS is presented. Famoxadone residues in spinach were extracted with acetonitrile and an aliquot was cleaned up with PSA (primary and secondary amine, Si-(CH2) 3-NH-(CH2)2-NH2) and C18 sorbent, which were powder material. Chiral stationary phase (CSP), cellulose tris(3,5-dimethylphenylcarbamate), was successfully applied to separate two enantiomers using methanol/formic acid-ammonium acetate buffer as mobile phase. The MS/MS fragmentation pathway of ammonium adduct famoxadone molecules ion at m/z 392 was analyzed and an odd electron fragment ion at m/z 238 was observed. Excellent linearity was achieved for each enantiomer over a range of concentrations from 0.5 to 1500 μg/L with coefficients more than 0.99. Average recoveries at five different levels (1, 2.5, 12.5, 250 and 1250 μg/kg, for each enantiomer) ranged from 80.8 to 96.5% with RSD of 4.8-13.4%. The famoxadone enantiomers LODs in spinach were determined to be both 0.3 μg/kg with LOQs of 1 μg/kg. Based on this method, the dissipation process of famoxadone enantiomers in spinach under open field and greenhouse conditions was characterized, providing guidance to the proper and safe use of this fungicide in agriculture.

  • 相关文献

[1]Enantioselective degradation of Myclobutanil and Famoxadone in grape. Lin, Chunmian,Zhang, Lijun,Zhang, Hu,Wang, Qiang,Zhu, Jiahong,Wang, Jianmei,Qian, Mingrong. 2018

[2]Different Enantioselective Degradation of Pyraclofos in Soils. Zhang, Hu,Qian, Mingrong,Xu, Yuxin,Yu, Man,Xiao, Hua,Zhuang, Shulin.

[3]Analysis of Tebuconazole and Tetraconazole Enantiomers by Chiral HPLC-MS/MS and Application to Measure Enantioselective Degradation in Strawberries. Zhang, Hu,Wang, Minghua,Zhang, Hu,Qian, Mingrong,Wang, Xinquan,Wang, Xiangyun,Xu, Hao,Qi, Peipei,Wang, Qiang.

[4]Enantioselective developmental toxicity and immunotoxicity of pyraclofos toward zebrafish (Danio rerio). Zhuang, Shulin,Zhang, Zhisheng,Zhang, Wenjing,Bao, Lingling,Zhuang, Shulin,Zhang, Wenjing,Bao, Lingling,Xu, Chao,Zhang, Hu.

[5]Residue Analysis and Degradation Studies of Fenbuconazole and Myclobutanil in Strawberry by Chiral High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Zhang, Hu,Wang, Xinquan,Qian, Mingrong,Wang, Xiangyun,Xu, Hao,Xu, Mingfei,Wang, Qiang.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：浙江省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台