Low-level expression of cholesterol 7 alpha-hydroxylase is associated with the formation of goose fatty liver
文献类型: 外文期刊
作者: Zhao, A. Y. 1 ; Wang, X. D. 2 ; Chen, G. H. 1 ; Lu, L. Z. 3 ;
作者机构: 1.Yangzhou Univ, Coll Anim Sci & Technol, Yangzhou 225009, Jiangsu, Peoples R China
2.Zhejiang Agr & Forestry Univ, Dept Anim Sci, Hangzhou 311300, Zhejiang, Peoples R China
3.Zhejiang Acad Agr Sci, Inst Anim Husb & Vet, Hangzhou 310021, Zhejiang, Peoples R China
关键词: triglyceride;low density lipoprotein: LDL;cholic acid: 81-25-4;synthesis;cholesterol: 57-88-5;catabolism;cholesterol 7-alpha-hydroxylase: 9037-53-0;expression;EC 1.14.13.17
期刊名称:POULTRY SCIENCE ( 影响因子:3.352; 五年影响因子:3.679 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: Cholesterol 7 alpha-hydroxylase (Cyp7a1) plays a crucial role in the synthesis of cholic acid and cholesterol catabolism. In this study, Cyp7a1 expression in goose liver was identified for the first time using differential display reverse transcription PCR. This study used real-time PCR and quantified the transcript levels of the cyp7a1 gene under different feeding conditions. In overfeeding, cyp7a1 expression by the liver was lower than that seen for normal feeding and the same result was observed for the Cyp7a1 protein level. The cholesterol level in serum and liver was higher in the overfed group. This study suggests that low-level expression of Cyp7a1 is associated with the formation of goose fatty liver.
- 相关文献
作者其他论文 更多>>
-
Effects of parental dietary linoleic acid on growth performance, antioxidant capacity, and lipid metabolism in domestic pigeons (Columba livia)
作者:Xu, Q. Q.;Ma, X. W.;Dong, X. Y.;Zou, X. T.;Tao, Z. R.;Lu, L. Z.;Tao, Z. R.;Lu, L. Z.
关键词:linoleic acid; growth performance; lipid metabolism; pigeon; parental dietary
-
Gene Expression Patterns of Geese Expression Patterns of L-Fabp, Spot 14, Ob and Apo A1 Genes in Different Tissues of Overfed and Control Geese
作者:Ma, Y. F.;Chen, L.;He, J.;Tian, Y.;Xu, X. Q.;Du, X.;Lu, L. Z.
关键词:Langde goose;lipids related genes;gene expression;fatty liver
-
Molecular cloning, expression, and regulation of estrogen receptors in pigeon oviduct epithelial cells
作者:Zhang, H.;Chen, F.;Tao, Z. R.;Li, J. J.;Lu, L. Z.;Zhang, H.;Chen, F.;Li, G. L.;Ding, Y. Y.;Zhong, S. L.
关键词:Estrogen receptor;Estrogen expression;siRNA;Estrogen regulation;Oviduct epithelial cells
-
Molecular cloning, expression, and regulation of the ovalbumin gene in pigeon oviduct epithelial cells
作者:Zhang, H.;Chen, F.;Liu, Y. L.;Yan, P. S.;Zhang, H.;Lu, L. Z.;Chen, L.;Tao, Z. R.;Chen, F.;Liu, Y. L.;Tian, Y.;Zhong, S. L.
关键词:Pigeon;Ovalbumin expression;Ovalbumin regulation;Pigeon oviduct epithelial cells;Steroid hormones
-
RNA interference of leptin receptor in chicken adipocytes
作者:Huang, A. X.;Fu, Y.;Wu, T. X.;Huang, A. X.;Li, J. J.;Tian, Y.;Shen, J. D.;Tao, Z. R.;Li, G. Q.;Lu, L. Z.
关键词:RNA interference;Leptin receptor;Chicken;Adipocyte;Lipid metabolism
-
Characterisation of 57 novel microsatellite markers from the goose (Anser cygnoides) genome
作者:Li, Jin Jun;Li, G. Q.;Shen, J. D.;Tao, Z. R.;Wang, D. Q.;Tian, Y.;Chen, L.;Yuan, Q. Y.;Lu, L. Z.;Shen, J. L.
关键词:Anser cygnoides;goose;microsatellite marker;enriched library;polymorphism
-
Construction and analysis of a subtractive cDNA library of early embryonic development in duck
作者:Liu, Y. L.;Zhong, L. X.;Shi, F. X.;Liu, Y. L.;Zhong, L. X.;Li, J. J.;Shen, J. D.;Wang, D. Q.;Tao, Z. R.;Lu, L. Z.
关键词:Duck;Embryo development;Subtractive hybridization;Duplex-specific nuclease;Nanog