您好，欢迎访问江苏省农业科学院 机构知识库！
江苏省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Gene Body Methylation in Plants: Mechanisms, Functions, and Important Implications for Understanding Evolutionary Processes

文献类型： 外文期刊

作者： Muyle, Aline M. 1 ; Seymour, Danelle K. 3 ; Lv, Yuanda 4 ; Huettel, Bruno 5 ; Gaut, Brandon S. 1 ;

作者机构： 1.Univ Calif Irvine, Ecol & Evolutionary Biol, Irvine, CA 92697 USA

2.Univ Lyon 1, Lab Biometrie & Biol Evolut, CNRS, Lyon, France

3.Univ Calif Riverside, Bot & Plant Sci, Riverside, CA USA

4.Jiangsu Acad Agr Sci, Inst Crop Germplasm & Biotechnol, Prov Key Lab Agrobiol, Nanjing, Peoples R China

5.Max Planck Genome Ctr Cologne, Max Planck Inst Plant Breeding, Cologne, Germany

关键词： epigenetics; gene expression; transcription; DNA methylation; population epigenomics

期刊名称：GENOME BIOLOGY AND EVOLUTION （ 影响因子：4.065； 五年影响因子：4.216 ）

ISSN： 1759-6653

年卷期： 2022 年 14 卷 4 期

页码：

收录情况： SCI

摘要： Gene body methylation (gbM) is an epigenetic mark where gene exons are methylated in the CG context only, as opposed to CHG and CHH contexts (where H stands for A, C, or T). CG methylation is transmitted transgenerationally in plants, opening the possibility that gbM may be shaped by adaptation. This presupposes, however, that gbM has a function that affects phenotype, which has been a topic of debate in the literature. Here, we review our current knowledge of gbM in plants. We start by presenting the well-elucidated mechanisms of plant gbM establishment and maintenance. We then review more controversial topics: the evolution of gbM and the potential selective pressures that act on it. Finally, we discuss the potential functions of gbM that may affect organismal phenotypes: gene expression stabilization and upregulation, inhibition of aberrant transcription (reverse and internal), prevention of aberrant intron retention, and protection against TE insertions. To bolster the review of these topics, we include novel analyses to assess the effect of gbM on transcripts. Overall, a growing body of literature finds that gbM correlates with levels and patterns of gene expression. It is not clear, however, if this is a causal relationship. Altogether, functional work suggests that the effects of gbM, if any, must be relatively small, but there is nonetheless evidence that it is shaped by natural selection. We conclude by discussing the potential adaptive character of gbM and its implications for an updated view of the mechanisms of adaptation in plants.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：江苏省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台