文献类型： 外文期刊
作者： Salman, Khan 1 ; Zhu, Hongjie 1 ; Sun, Ziqian 1 ; Li, Yilin 3 ; Wang, Lan 1 ; Wang, Rong 4 ; Guo, Zhikai 2 ; Jiao, Ruihua 1 ;
作者机构： 1.Nanjing Univ, Inst Funct Biomol, Sch Life Sci, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Trop Microbe Resources, Haikou 571101, Peoples R China
3.Hainan Inst Trop Agr Resources, Key Lab Biol & Genet Resources Trop Crops Hainan P, Haikou 571101, Peoples R China
4.Hainan Trop Ocean Univ, Hainan Acad Ocean & Fisheries Sci, Haikou 571126, Peoples R China
关键词： Fungus; Sesquiterpenoids; Drimane-type; Antibacterial; Cytotoxic; Aspergillus sp
期刊名称：CHINESE JOURNAL OF NATURAL MEDICINES （ 影响因子：4.6； 五年影响因子：3.8 ）
ISSN： 2095-6975
年卷期： 2023 年 21 卷 1 期
页码：
收录情况： SCI
摘要： Drimane-type sesquiterpenoids are widely distributed in fungi. From the ethyl acetate extract of the earwig-derived As-pergillus sp. NF2396, seven new drimane-type sesquiterpenoids, named drimanenoids A-G (1-7), were isolated. Their structures were elucidated by diverse spectroscopic analysis including high-resolution ESI-MS, one-and two-dimensional NMR spectroscopy. Drim-anenoids A-F (1-6) are new members of drimane-type sesquiterpenoid esterified with unsaturated fatty acid side chain at C-6. Drim-anenoids C (3), D (4) and F (6) showed antibacterial activity against five types of bacteria with different inhibition diameters. Drim-anenoid D (4) exhibited moderate cytotoxicity against human myelogenous leukemia cell line K562 with an IC50 value of 12.88 +/- 0.11 mu mol center dot L-1.
- 相关文献
作者其他论文 更多>>
-
Thiolutin Is a Potential Fungicide for Controlling Phytophthora nicotianae and Its Mechanistic Study
作者：Xu, Gang;Huang, Xing;Liang, Yanqiong;Tan, Shibei;Chen, Helong;Yi, Kexian;Wu, Weihuai;Xu, Gang;Ma, Xiang;Xiong, Zijun;Guo, Zhikai;Xiong, Zijun;Guo, Zhikai
关键词：
Phytophthora nicotianae ; thiolutin; antifungal activity; mitochondria bursting -
Kitasatospora hibisci sp. nov., a novel actinomycete with antimicrobial potential isolated from rhizosphere soil of Hibiscus tiliaceus in Guangxi
作者：Xiao, Jinlan;Luo, Shenhao;Lu, Shiqi;Hong, Zhiwei;Huang, Xiaolong;Lin, Yongrui;Zhou, Shuangqing;Wang, Jiyang;Guo, Zhikai;Guo, Zhikai
关键词：antimicrobial potential; Hibiscus tiliaceus; Kitasatospora hibisci sp. nov.; polyphasic taxonomy
-
Critical Secondary Metabolites Confer the Broad-Spectrum Pathogenic Fungi Resistance Property of a Marine-Originating Streptomyces sp. HNBCa1
作者：Xiong, Zijun;Wu, Weicheng;Qi, Min;Zhang, Shiqing;Guo, Zhikai;Xia, Tengfei;Zheng, Daojun;Wu, Weicheng;Qi, Min;Li, Jitao;Wang, Rong;Yang, Yang;Lin, Shuangjun
关键词：broad-spectrum resistance; secondary metabolites; pathogenic fungi; antifungal activity; biocontrol
-
Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1a/XBP-1s axis and JNK signaling
作者：Rao, Yong;Su, Rui;Wu, Chenyan;Yang, Guanyu;Wu, Junjie;Fu, Tingting;Jiang, Zhongping;Xu, Congjun;Huang, Ling;Guo, Zhikai;Guo, Zhikai;Li, Jinjian;Chai, Xingxing
关键词：Lipotoxicity; MAFLD; ER stress; IRE-1a; XBP-1s; JNK; PLA2
-
Secondary Metabolites with Agricultural Antagonistic Potential from Aspergillus sp. ITBBc1, a Coral-Associated Marine Fungus
作者：Abulaizi, Ailiman;Ge, Huiming;Wang, Rong;Xiong, Zijun;Zhang, Shiqing;Guo, Zhikai;Wang, Rong;Xiong, Zijun;Zhang, Shiqing;Guo, Zhikai;Wang, Rong;Li, Yuanchao
关键词：Aspergillus sp.; marine fungi; secondary metabolites; phytotoxic activity
-
Natural Products and Biological Activity from Actinomycetes Associated with Marine Algae
作者：Xiong, Zijun;Zhang, Shiqing;Ma, Shuai;Guo, Zhikai;Xiong, Zijun;Zhang, Shiqing;Ma, Shuai;Guo, Zhikai;Wang, Rong;Xia, Tengfei
关键词：actinomycetes; marine algae; secondary metabolite; bioactive compound
-
New Isocoumarin and Pyrone Derivatives from the Chinese Mangrove Plant Rhizophora mangle-Associated Fungus Phomopsis sp. DHS-11
作者：Guo, Zhikai;Chen, Biting;Yuan, Jingzhe;Zhang, Shiqing;Xiong, Zijun;Guo, Zhikai;Chen, Biting;Yuan, Jingzhe;Zhang, Shiqing;Xiong, Zijun;Chen, Biting;Chen, Dandan;Deng, Xiaoling;Xu, Jing
关键词：mangrove; endophytic fungus; Phomopsis sp.; polyketides; cytotoxic activity
