文献类型： 外文期刊

作者： Shen, AQ ¹ ; Zhong, HJ ² ; Zheng, H ² ; Zhang, HY ² ; Zhao, GH ² ; Wu, QA ² ; Mao, HY ² ; Wang, EB ² ; Zhu, Y ² ;

作者机构： 1.NE Normal Univ, Coll Chem, Changchun 130024, Peoples R China

2.NE Normal Univ, Coll Chem, Changchun 130024, Peoples R China; Henan Acad Agr Sci, Ctr Expt Res, Zhengzhou 450008, Peoples R China; Zhengzhou Univ, Dept Chem, Zhengzhou 450052, Peoples R China

关键词： 1.3;4-thiadiazole;zinc;crystal structure;thermal decomposition;kinetics;bioactivity

期刊名称：POLYHEDRON （ 影响因子：3.052； 五年影响因子：2.274 ）

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收录情况： SCI

摘要： The synthesis and characterization of a Zn(II) complex with 5-ethyl-2-amino-1,3,4-thiadiazole (eatz) are described. The crystal structure of [Zn(eatz)(2)(OAC)(2)] was determined by X-ray diffraction. The crystal belongs to the monoclinic system and the structural unit is a distorted tetrahedron. In this complex, eatz acts as a monodentate ligand coordinating through the thiadiazole N atom to Zn(II), and the crystal structure is mainly stabilized by both intra- and intermolecular hydrogen bonds. Thermal analysis reveals that the complex [Zn(eatz)(2)(OAC)(2)] decomposes in three transitions to give Zn(CN)(2) as the end product at 650 degreesC in N-2 atmosphere. The thermal decomposition kinetic analysis of the title complex indicates that the first transition is a double-step reaction with the main reaction being an nth auto-catalysis one. A biological activity study shows that both the ligand and the complex have good antimicrobial activities against Staphylococcus aureus. (C) 2004 Published by Elsevier Ltd.