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Acid-promoted synthesis of pyrazolo[4,3-c]quinoline derivatives by employing pyrazole-arylamines and beta-keto esters via cleavage of C-C bonds

文献类型: 外文期刊

作者: Jiang, Rui 1 ; Mu, Yangxiu 1 ; Zhang, Wei 2 ; Hong, Yu 1 ; Iqbal, Zafar 1 ; Hou, Jing 1 ; Yang, Zhixiang 1 ; Tang, Dong 1 ;

作者机构: 1.Ningxia Acad Agr & Forestry Sci, Inst Agr Resources & Environm, Yinchuan, Ningxia, Peoples R China

2.Ningxia Acad Agr & Forestry Sci, Yinchuan, Ningxia, Peoples R China

关键词: Acid-promoted; cleavage of C-C bonds; beta-keto esters; pyrazolo[4,3-c]quinoline; pyrazole-arylamines

期刊名称:SYNTHETIC COMMUNICATIONS ( 影响因子:1.937; 五年影响因子:1.794 )

ISSN: 0039-7911

年卷期: 2022 年 52 卷 18 期

页码:

收录情况: SCI

摘要: An approach for the synthesis of pyrazolo[4,3-c]quinoline derivatives has been developed by the combination of pyrazole-arylamines and beta-keto esters via cleavage of C-C bonds. The strategy shows good tolerance and compatibility with a wide range of functional groups. Moreover, this method features simple conditions, generates a series of alkyl substituted pyrazolo[4,3-c]quinoline, and provides the desired products in moderate to good yields. [GRAPHICS] .

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