文献类型： 外文期刊
作者： Li, Erna 1 ; Li, Shipei 1 ; Wang, Siyuan 1 ; Li, Qian 1 ; Pang, Daorui 1 ; Yang, Qiong 1 ; Zhu, Qiaoling 2 ; Zou, Yuxiao 1 ;
作者机构： 1.Guangdong Acad Agr Sci, Sericultural & Agrifood Res Inst, Key Lab Funct Foods, Guangdong Key Lab Agr Prod Proc,Minist Agr & Rural, Guangzhou 510610, Peoples R China
2.South China Agr Univ, Coll Food Sci, Guangzhou, Peoples R China
关键词： Ramulus mori oligosaccharides; Streptococcus mutans; anti-caries; antibacterial; biofilm
期刊名称：FOODS （ 影响因子：5.2； 五年影响因子：5.5 ）
ISSN：
年卷期： 2023 年 12 卷 17 期
页码：
收录情况： SCI
摘要： Ramulus mori has been widely used in traditional Chinese medicine because of its physiological activities, including antibacterial, anti-inflammatory, and antioxidant activities. Antimicrobial properties of Ramulus mori extract have been well described. However, no information is available regarding on Ramulus mori oligosaccharides (RMOS). The aim of this study was to investigate the effects of RMOS on the growth and virulence properties of the cariogenic bacterium Streptococcus mutans. The effects of RMOS on the biofilm structure and virulence gene expression of S. mutans were also evaluated, and the results were compared with the effects of commercial prebiotic galactooligosaccharides. RMOS were found to have an antibacterial effect against S. mutans, resulting in significant reductions in acid production, lactate dehydrogenase activity, adhesion, insoluble extracellular polysaccharide production, glucosyltransferase activity, and biofilm formation in a dose-dependent manner. Moreover, the biofilm structure was visibly damaged. A quantitative real-time PCR assay revealed downregulation of virulence gene-regulated acid production, polysaccharide production, adhesion, biofilm formation, and quorum sensing. These findings suggest that RMOS may be a promising natural product for the prevention of dental caries.
- 相关文献
作者其他论文 更多>>
-
Targeted and non-targeted metabolic characteristics of 6,7-dihydroxy-2,4-dimethoxyphenanthrene during simulated gastrointestinal digestion
作者：Li, Qian;Liu, Fan;Liao, Sentai;Zhou, Donglai;Xing, Dongxu;Zou, Yuxiao
关键词：Phenanthrenes; Chinese yam; Gastrointestinal digestion; Characteristic metabolism
-
Dietary supplementation of mulberry leaf oligosaccharides improves the growth, glucose and lipid metabolism, immunity, and virus resistance in largemouth bass (Micropterus salmoides)
作者：Zhou, Donglai;Zhong, Wenhao;Fu, Bing;Li, Erna;Li, Qingrong;Yang, Qiong;Zou, Yuxiao;Liao, Sentai;Xing, Dongxu;Zhou, Donglai;Li, Erna;Wang, Fubao;Zhong, Wenhao;Hao, Le;Liu, Zhenxing
关键词：largemouth bass; growth; serum biochemistry; liver metabolism; inflammation
-
Mulberry leaf extract reduces damage by regulating the oxidative response, immune response and intestinal flora of largemouth bass (Micropterus salmoides) under chronic heat stress
作者：Fu, Bing;Zhou, Donglai;Qiu, Xiaotong;Zheng, Jieqiu;Yang, Qiong;Xiao, Yang;Liao, Sentai;Li, Qingrong;Xing, Dongxu;Qiu, Xiaotong;Zheng, Jieqiu
关键词：mulberry leaf extract; largemouth bass; heat stress; intestinal flora; liver injury; immune ability
-
Inhibition Mechanism of Mulberry Prenylated Flavonoids Sanggenone D/Kuwanon G Against α-Glucosidase and the Regulation of Glucose via GLUT4 Pathway
作者：Wu, Erwen;Zhu, Yanqing;Zou, Yuxiao;Liu, Fan;Li, Qian;Wu, Erwen;Wei, Qingyi;Lu, Huijie;Li, Qian
关键词：alpha-glucosidase; inhibition mechanisms; molecular docking; Western blotting; structure-activity relationship
-
Hsp70-mediated manipulation of antimicrobial peptide-related genes promotes BmNPV proliferation in Bombyx mori at relatively high temperatures
作者：Zhang, Jie;Hu, Yingying;Feng, Jiawei;He, Na;Li, Xiaofeng;Liyi, Qingge;Yi, Huiyu;Yang, Wanying;Zhang, Jie;Yang, Qiong
关键词：Bombyx mori; BmNPV; Innate immunity; Host-pathogen interaction; Heat shock protein (Hsp); Antimicrobial peptide (AMP)
-
Comparative study of intelligent sensory technologies combined multiple metabolomics in evaluating sensory attributes and health profiles across different grades and varieties of green tea-processed mulberry leaf tea
作者：Lin, Junhui;Yang, Zhangchang;Li, Qian;Wang, Weifei;Liao, Sentai;Xing, Dongxu;Pang, Daorui;Zou, Yuxiao;Chen, Ruohong
关键词：Mulberry leaf tea; After frost; Different grades; Volatile metabolites; Nonvolatile metabolites; Bioactive substances; Lignans; Intelligent sensory technologies
-
Metabolomics-based analysis of the effects of differences in soluble sugars on the sweetness quality of six major tea types in China
作者：Li, Wen;Chen, Zhongzheng;Zhang, Zhenbiao;Chen, Ruohong;Sun, Lingli;Lai, Xingfei;Li, Qiuhua;Hao, Mengjiao;Zhang, Suwang;Sun, Shili;Li, Qian
关键词：
