文献类型： 外文期刊

作者： Zhao, Lei ¹ ; Zheng, Ya-Guang ³ ; Feng, Yong-Hui ⁴ ; Li, Mu-Yang ¹ ; Wang, Gui-Qin ² ; Ma, Yan-Fen ⁵ ;

作者机构： 1.Heilongjiang Bayi Agr Univ, Coll Anim Sci & Vet Med, Daqing 163316, Heilongjiang, Peoples R China

2.Jilin Agr Univ, Coll Anim Sci & Technol, Changchun 130118, Jilin, Peoples R China

3.Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot 010018, Peoples R China

4.Kailu Livestock Improvement Workstn, Tongliao 028400, Inner Mongolia, Peoples R China

5.Inner Mongolia Acad Agr & Anim Husb Sci, Inst Anim Nutr & Feed, Hohhot 010031, Inner Mongolia, Peoples R China

关键词： Pb; Oxidative stress; Immune response; HSPs gene expression

期刊名称：CHEMOSPHERE （ 影响因子：7.086； 五年影响因子：6.956 ）

ISSN： 0045-6535

年卷期： 2020 年 261 卷

页码：

收录情况： SCI

摘要： Lead (Pb) is a harmful metal element for aquatic animals. The aim of this study was to determine waterborne Pb exposure on oxidative stress, serum biochemistry and heat shock proteins (HSPs) genes expression in Channa argus. Fish were randomly divided into four groups and the Pb concentrations were 0, 50, 200, and 800 mu g/L, respectively. The results showed that the accumulation of Pb was detected in the gill, intestine, liver and muscle following exposure to Pb. Pb accumulation content in tissues was gill > intestinal > liver > muscle. With the increased of Pb exposure concentrations, the levels of catalase (CAT), glutathione peroxidase (GPx), lysozyme (LZM) and immunoglobulin M (IgM) significantly decreased. Serum biochemistry, oxidative stress parameters and HSPs gene expression were all enhanced with the increase following Pb expose concentration. Our results suggest that waterborne Pb exposure can induce Pb accumulation, oxidative stress and immune response in C. argus. (C) 2020 Elsevier Ltd. All rights reserved.