MoSec61 beta, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae
文献类型： 外文期刊
作者： Wei, Yun-Yun 1 ; Liang, Shuang 2 ; Zhang, Yun-Ran 1 ; Lu, Jian-Ping 4 ; Lin, Fu-Cheng 1 ; Liu, Xiao-Hong 1 ;
作者机构： 1.Zhejiang Univ, Inst Biotechnol, State Key Lab Managing Biot & Chem Treats Qual &, Hangzhou, Peoples R China
2.Westlake Univ, Sch Life Sci, Zhejiang Prov Lab Life Sci & Biomed, Key Lab Struct Biol Zhejiang Prov, Hangzhou, Peoples R China
3.Westlake Inst Adv Study, Inst Basic Med Sci, Hangzhou, Peoples R China
4.Zhejiang Univ, Coll Life Sci, Hangzhou, Peoples R China
5.Zhejiang Acad Agr Sci, Inst Plant Protect & Microbiol, State Key Lab Managing Biot & Chem Treats Qual &, Hangzhou, Peoples R China
关键词： Sec61β development; pathogenesis; plant immunity; ER-phagy
期刊名称：VIRULENCE （ 影响因子：5.882； 五年影响因子：6.489 ）
ISSN： 2150-5594
年卷期： 2020 年 11 卷 1 期
页码：
收录情况： SCI
摘要： The process of protein translocation into the endoplasmic reticulum (ER) is the initial and decisive step in the biosynthesis of all secretory proteins and many soluble organelle proteins. In this process, the Sec61 complex is the protein-conducting channel for transport. In this study, we identified and characterized the beta subunit of the Sec61 complex in Magnaporthe oryzae (MoSec61 beta). Compared with the wild-type strain Guy11, the Delta Mosec61 beta mutant exhibited highly branched mycelial morphology, reduced conidiation, high sensitivity to cell wall integrity stress, severely reduced virulence to rice and barley, and restricted biotrophic invasion. The turgor pressure of Delta Mosec61 beta was notably reduced, which affected the function of appressoria. Moreover, Delta Mosec61 beta was also sensitive to oxidative stress and exhibited a reduced ability to overcome plant immunity. Further examination demonstrated that MoSec61 beta affected the normal secretion of the apoplastic effectors Bas4 and Slp1. In addition, Delta Mosec61 beta upregulated the level of ER-phagy. In conclusion, our results demonstrate the importance of the roles played by MoSec61 beta in the fungal development and pathogenesis of M. oryzae.
- 相关文献
作者其他论文 更多>>
-
iDIA-QC: AI-empowered data-independent acquisition mass spectrometry-based quality control
作者：Gao, Huanhuan;Zhu, Yi;Wang, He;Xie, Yuting;Sun, Yingying;Jiang, Wenhao;Dong, Zhen;Qian, Liqin;Guo, Tiannan;Gao, Huanhuan;Zhu, Yi;Wang, He;Xie, Yuting;Sun, Yingying;Jiang, Wenhao;Dong, Zhen;Qian, Liqin;Guo, Tiannan;Gao, Huanhuan;Zhu, Yi;Wang, He;Xie, Yuting;Sun, Yingying;Jiang, Wenhao;Dong, Zhen;Qian, Liqin;Guo, Tiannan;Wang, Dongxue;Wang, Guibin;He, Fuchu;Wang, Dongxue;He, Fuchu;Nie, Zongxiang;Liang, Shuang;Wang, Xufei;Liang, Mengdi;Chen, Min;Fang, Houqi;Zeng, Qiufang;Tian, Jiao;Sun, Zeyu;Xue, Juan;Li, Shan;Xue, Juan;Li, Shan;Chen, Chen;Liu, Xiang;Lyu, Xiaolei;Kong, Fengchun;Guo, Zhenchang;Qi, Yingzi;Tong, Tingde;Wu, Ruoyu;Du, Xiaoxian;Han, Liming;Wang, Minghui;Zhao, Yang;Dai, Xinhua
关键词：
-
The endosomal-vacuolar transport system acts as a docking platform for the Pmk1 MAP kinase signaling pathway in Magnaporthe oryzae
作者：Wang, Qing;Huang, Zhicheng;Li, Yan;Li, Hui;Lin, Fu-Cheng;Lu, Jianping;Wang, Jing;Cai, Yingying;Wang, Jiaoyu;Lin, Fu-Cheng;Huang, Pengyun;Liu, Xiaohong;Lin, Fu-Cheng
关键词：appressorium; endosome; MAPK; Pmk1; rice blast fungus; signal; ubiquitination; vacuole
-
A multilayered regulatory network mediated by protein phosphatase 4 controls carbon catabolite repression and de-repression in Magnaporthe oryzae
作者：Huang, Zhicheng;Wang, Qing;Li, Yan;Li, Hui;Lin, Fu-Cheng;Lu, Jianping;Huang, Pengyun;Liao, Jian;Liu, Xiaohong;Lin, Fu-Cheng;Wang, Jing;Cai, Yingying;Wang, Jiaoyu;Lin, Fu-Cheng
关键词：
-
Comparative functional analysis of a new CDR1-like ABC transporter gene in multidrug resistance and virulence between Magnaporthe oryzae and Trichophyton mentagrophytes
作者：Wang, Jing;Xiao, Chenwen;Liang, Shuang;Noman, Muhammad;Cai, Yingying;Zhang, Zhen;Zhu, Xueming;Chai, Rongyao;Qiu, Haiping;Hao, Zhongna;Wang, Yanli;Wang, Jiaoyu;Sun, Guochang;Lin, Fucheng;Bao, Guolian
关键词：
MoCDR1 ;TmCDR1 ; ABC transporters;Magnaporthe oryzae ;Trichophyton mentagrophytes -
MoSec13 combined with MoGcn5b modulates MoAtg8 acetylation and regulates autophagy in Magnaporthe oryzae
作者：Qian, Hui;Wu, Ming-Hua;Zhao, Wen-Hui;Lin, Fu-Cheng;Liu, Xiao-Hong;Zhu, Xue-Ming;Lin, Fu-Cheng;Zhu, Xue-Ming;Lin, Fu-Cheng;Sun, Li-Xiao;Lu, Jian-Ping;Klionsky, Daniel J.
关键词：Autophagy; Gcn5b;
Magnaporthe oryzae ; Sec13; TORC2 -
The whole genome sequence of Cordyceps cicadae - an edible and potential medicinal fungus
作者：Liu, Yuwei;Li, Xueqian;Meng, Yiqi;Zhou, Wei;Lin, Fu-Cheng;Wang, Hongkai;Lin, Fu-Cheng;Wu, Yifan;Jin, Yuting;Ma, Xiaotong;Tan, Yuchong
关键词：
Cordyceps cicadae ; Whole genome; Hi-C sequencing -
Bacterial extracellular biomolecules-derived multimodal manganese nanoparticles control watermelon Fusarium wilt by dysregulating fusaric acid biosynthesis pathway and precise tuning of rhizosphere metabolome
作者：Noman, Muhammad;Islam, Mohammad Shafiqul;Wang, Jing;Cai, Yingying;Hao, Zhongna;Qiu, Haiping;Zhang, Zhen;Chai, Rongyao;Wang, Yanli;Wang, Jiaoyu;Ahmed, Temoor;Ahmed, Temoor;Islam, Mohammad Shafiqul;Li, Bin;Liang, Shuang;Ali, Hayssam M.
关键词：Fusaric acid; Fusarium wilt; Manganese nanoparticles; Rhizosphere metabolome; Watermelon
