文献类型： 外文期刊

作者： Chai, Danxia ¹ ; Liu, Wenxin ² ; Hao, Xiufeng ¹ ; Wang, Heyuan ³ ; Wang, Haixiao ¹ ; Hao, Yujiao ¹ ; Gao, Yue ² ; Qu, Hui ¹ ;

作者机构： 1.Jilin Univ, Coll Chem, Dept Polymer Sci, Changchun 130012, Peoples R China

2.Inner Mongolia Univ, Coll Chem & Chem Engn, Hohhot 010021, Peoples R China

3.First Hosp Jilin Univ, Dept Endocrinol & Metab, Changchun 130021, Jilin, Peoples R China

4.Minist Agr, Inner Mongolia Acad Agr & Anim Husb Sci, Lab Qual & Safety Risk Assessment Agr Prod Hohhot, Hohhot 010031, Peoples R China

关键词： Magnetic nanoparticles; N-halamine coating; Dopamine; Mussel-inspired; Antibacterial use

期刊名称：COLLOID AND INTERFACE SCIENCE COMMUNICATIONS （ 影响因子：4.914； 五年影响因子：4.172 ）

ISSN： 2215-0382

年卷期： 2020 年 39 卷

页码：

收录情况： SCI

摘要： Antibacterial N-halamine coatings are successful in avoiding and eliminating bacterial infections caused by bacterial contamination and biofilms on the surfaces. However, the N-halamine coatings remain a long-standing challenge faced by our healthcare system. Herein we reported a new mussel-inspired surface modification strategy to achieve N-halamine copolymer coatings with adhesive effects. The phenolic hydroxyl groups from Nhalamine copolymers are used for ligand exchange with oleic acid on the magnetic Fe3O4 nanoparticles for binding the N-halamine copolymer onto the surface of the nanoparticles. The as-synthesized N-halamine coatings endow the magnetic Fe3O4 nanoparticles antibacterial activity toward both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). Since the super-paramagnetism of Fe3O4 in core, the N-halamine coatings are separable magnetically and remain high inactivating efficiency toward bacteria even after five cycles. We believe that, with the advantage of mussel-inspired strategy, the N-halamine coatings should have great potential for use in antibacterial and biomedical fields.