您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

The immune efficacy of a Streptococcus agalactiae immersion vaccine for different sizes of young tilapia

文献类型： 外文期刊

作者： Ke, Xiaoli 1 ; Liu, Zhigang 1 ; Chen, Shanzhen 2 ; Chen, Zhiting 1 ; Zhang, Defeng 1 ; Gao, Fengying 1 ; Lu, Maixin 1 ;

作者机构： 1.Chinese Acad Fishery Sci, Key Lab Trop & Subtrop Fishery Resource Applicat, Key Lab Aquat Anim Immune Technol Guangdong Prov, Pearl River Fisheries Res Inst,Minist Agr, Guangzhou 510380, Peoples R China

2.Guangdong Haid Inst Anim Husb & Vet, Guangzhou 511400, Peoples R China

关键词： Immersion vaccine; Immunohistochemistry; Streptococcus agalactiae; Young tilapia

期刊名称：AQUACULTURE （ 影响因子：4.242； 五年影响因子：4.723 ）

ISSN： 0044-8486

年卷期： 2021 年 534 卷

页码：

收录情况： SCI

摘要： In order to explore the immune efficacy of a Streptococcus agalactiae immersion vaccine for young tilapia, three sizes of tilapia were selected and immunized a single time with an S. agalactiae immersion vaccine. The results that showed the whole cell antigen was crushed into nanoparticles and positive signals of antigen uptake were found in different sizes of tilapia and were mainly distributed in the gill, oropharynx, kidney, liver, spleen, intestine, and fish skin. The relative peak expression values for IgM, IgT, CD8+, and C3 from 1 g tilapia were significantly higher than those in 0.1 g and 0.5 g groups (P < 0.05). The differential expression of IgT was most significant, and the peak expression of C3 was maintained the longest time. The antibody level peak values appeared in 0.5 g and 1 g groups at the second week post-vaccination; both were significantly higher than that in 0.1 g tilapia (P < 0.05), and the higher antibody level in 1 g tilapia lasted longer than in the other two sizes. During the three months post-vaccination, the peak RPS in three different sizes of tilapia were all higher than 60% and the effective protection period in 1 g tilapia was longer than those of the 0.1 g and 0.5 g groups (P < 0.05). These results suggested that the immersion vaccine employed in the present study was effective against S. agalactiae infection for young tilapia (0.1-1 g) through one-time bath. In addition, the RPS and effective protection period in 1 g tilapia was higher and longer than those of the 0.1 g and 0.5 g groups.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台