Effects of Decabrominated Diphenyl Ether Exposure on Growth, Meat Characteristics and Blood Profiles in Broilers
文献类型： 外文期刊
作者： Liu, Zehui 1 ; Lei, Hulong 2 ; Tang, Renyong 3 ; Yang, Junhua 1 ; Guo, Xiulan 3 ; Huang, Renmao 1 ; Rao, Qinxiong 1 ; Che 1 ;
作者机构： 1.Shanghai Acad Agr Sci, Inst Agrofood Stand & Testing Technol, Shanghai 201403, Peoples R China
2.Shanghai Acad Agr Sci, Inst Anim Husb & Vet Sci, Shanghai 201106, Peoples R China
3.Chengdu Univ, Sch Pharm & Biol Engn, Chengdu 610106, Peoples R China
关键词： decabrominated diphenyl ether; toxicity assessment; meat characteristics; antioxidant capacity; broilers
期刊名称：ANIMALS （ 影响因子：2.752； 五年影响因子：2.942 ）
ISSN： 2076-2615
年卷期： 2021 年 11 卷 2 期
页码：
收录情况： SCI
摘要： Simple Summary Decabrominated diphenyl ether (BDE-209) has been widely used in recent decades, and its cumulative toxicity to crops, animals and human beings is attracting increasing attention. In this study, we established broiler models to investigate the effects of BDE-209 exposure at doses of 0, 0.02, 0.4 and 4 mg/kg on growth, carcass traits, meat quality, blood profiles and antioxidant capacity. Our results suggested that BDE-209 exposure altered the blood profiles and carcass traits and exhibited toxicity in liver and kidney functions. Furthermore, BDE-209 increased plasma malondialdehyde (MDA) concentrations and decreased the activities of glutathione peroxidase (GSH-px) and superoxide dismutase (SOD), which implied aggravating oxidant stress and decline of antioxidant capacity in broilers. Decabrominated diphenyl ether (BDE-209) is widely used as a flame retardant and is detected at high levels in the environment. Its toxicities have been reported and have attracted attention. In the present study, broilers were used to determine the response in growth performance, carcass traits, meat quality, blood profiles and antioxidant system to BDE-209 exposure at doses of 0, 0.02, 0.4 and 4 mg/kg. The results showed that BDE-209 exposure at levels of 0.02 or 0.4 mg/kg increased feed intake and decreased feed efficiency. BDE-209 altered the blood profiles, such as reducing the numbers of white blood cells, lymphocytes and neutrophilic granulocytes. As compared with the control, BDE-209 exposure significantly increased abdominal fat percentages of broilers at 64.9-159.5% and adversely affected the selected biochemical indicators, including alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine (CRE), which indicated its toxicity to liver and kidney functions. Moreover, BDE-209 exposure significantly increased plasma malondialdehyde (MDA) concentrations and decreased the activities of glutathione peroxidase (GSH-px) and superoxide dismutase (SOD), which implied aggravating oxidant stress and decline of antioxidant capacity in broilers. In conclusion, our data demonstrated that the environmental pollutant BDE-209 adversely influenced growth performance, increased the deposition of abdominal fat, impaired antioxidant capacity and the immune system and had potential toxicity to the liver and kidney of broilers.
- 相关文献
作者其他论文 更多>>
-
Combined Toxicity Assessment of Deoxynivalenol and Pb2+ on HK-2 Cells Involved in Excessive ROS-Induced Ferroptosis
作者：Zhu, Zuoyin;Wang, Jie;Cheng, Haisheng;Zhou, Xinli;Zhu, Zuoyin;Wang, Jie;Cheng, Haisheng;Zhao, Hanke;Liu, Chengbin;Yang, Junhua
关键词：ferroptosis; combined toxicity; mycotoxins; heavy metals
-
Occurrence of Co-Contamination and Interaction of Multi-Mycotoxins in Dairy Cow Feed in China
作者：Zhu, Zuoyin;Cheng, Haisheng;Wang, Jie;Zhou, Xinli;Zhu, Zuoyin;Cheng, Haisheng;Wang, Jie;Wang, Jianhua;Yang, Junhua;Ma, Junmei;Wang, Hongyang
关键词：feed; mycotoxin; co-contamination; correlation; interaction
-
Isotope Ratio Mass Spectrometry (IRMS)-Based Authentication of the Geographic Origins of Volvariella volvacea (Bull.) Singer
作者：Liu, Xing;Liu, Zhu;Li, Peijun;Liu, Xing;Rao, Qinxiong;Zhang, Qicai;Geng, Hao;Lu, Yangyang;Chen, Shanshan;Song, Weiguo;Liu, Xing;Rao, Qinxiong;Zhang, Qicai;Geng, Hao;Lu, Yangyang;Chen, Shanshan;Song, Weiguo;Liu, Zhu;Li, Peijun
关键词：
Volvariella volvacea ; stable isotope; nutrition component; geographic origin; PLS-DA -
Non-targeted metabolomics studies revealed the effects of environmentally relevant concentrations of perfluorooctane sulfonic acid (PFOS) on carbohydrate metabolism in red claw crayfish (Cherax quadricarinatus)
作者：Hong, Shuang;Liu, Chengbin;Liu, Xiaoyu;Rao, Qinxiong;Wang, Xianli;Zhang, Qicai;Yao, Chunxia;Song, Weiguo;Hong, Shuang
关键词：Perfluoroctane sulfonate; Environmental relevant concentration; Cherax quadricarinatus; Metabolomics; Carbohydrate metabolism
-
Enhanced Electrochemical and Photochemical Sensors for In Vivo Biological Monitoring Based on Carbon Nanomaterials
作者：Huang, Qingwen;Lin, Xialin;Nie, Dongxia;Wang, Jie;Fan, Kai;Zhao, Zhihui;Han, Zheng;Lin, Xialin;Zhao, Zhihui
关键词：carbon nanomaterials; electrochemical sensors; in vivo detection; photochemical sensor
-
Inhibition Effects of Infrared Radiation Prior to Cold Storage Against Alternaria alternata on Yellow Peach (Amygdalus persica)
作者：Liu, Longxiao;Li, Zhizhong;Liu, Longxiao;Fan, Kai;Huang, Qingwen;Wang, Xinyi;Nie, Dongxia;Han, Zheng;Zhao, Zhihui
关键词：
Alternaria alternata ;Alternaria toxins; infrared radiation; yellow peach; inhibitory effect -
Agaricus bisporus stipe fed to dairy heifers: effects on growth performance, immunity and antioxidant capacity, and rumen microbiota
作者：Jia, Peng;Jiang, Xueyuan;Lei, Hulong;Lu, Naisheng;Xia, Dong;Lu, Chunguang;Yang, Xingyu
关键词：heifers; mushrooms;
Agaricus bisporus ; growth performance; serum immunity; serum antioxidant; rumen microbiota
